2. Gene
  3. FLT3 - fms related receptor tyrosine kinase 3 Gene

FLT3 - fms related receptor tyrosine kinase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：fms 相关 受体酪氨酸激酶 3

种属: Sus scrofa

基因 ID: 100515445 | 基因类型: protein coding

关于 FLT3

Primary_assembly 11: 5,370,496-5,455,358 reverse strand.Sscrofa11.1:CM000822.5

This gene has 1 transcript (splice variant), 134 orthologues and 52 paralogues. Broad expression in spleen (RPKM 3.2), ovary (RPKM 2.6) and 6 other tissues.

FLT3 基因产物(2)

mRNA Protein Name
XM_021065521.1 XP_020921180.1 receptor-type tyrosine-protein kinase FLT3 isoform X1
XM_005668293.3 XP_005668350.1 receptor-type tyrosine-protein kinase FLT3 isoform X2

FLT3 蛋白结构

ig

ig: pfam00047 (255 - 344)

Ig

Ig: cd00096 (267 - 271)

Ig

Ig: cd00096 (281 - 285)

Ig

Ig: cd00096 (313 - 316)

Ig

Ig: cd00096 (326 - 331)

PKc_like

PKc_like: cl21453 (571 - 946)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 990 a.a.
蛋白主名 其他名称

receptor-type tyrosine-protein kinase FLT3

fms related tyrosine kinase 3

相关产品

Approval
生物活性分子 (13)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10201 Sorafenib Inhibitor 99.92% 是
HY-13016 Cabozantinib Inhibitor 99.96% 是
HY-12432 Gilteritinib Inhibitor 99.69% 是
HY-13001 Quizartinib Inhibitor 99.01% 是
HY-10201A Sorafenib Tosylate Inhibitor 99.91% 是
HY-16379 Pacritinib Inhibitor 99.93% 是
HY-13038A Fostamatinib Inhibitor 99.50% 是
HY-112306 Ripretinib Inhibitor 99.33% 是
HY-12432A Gilteritinib hemifumarate Inhibitor 99.75% 是
HY-10201S Sorafenib-d3 Inhibitor 99.57% 否
HY-13038 Fostamatinib Disodium Inhibitor 99.88% 是
HY-13038B Fostamatinib disodium hexahydrate Inhibitor 99.73% 是
HY-13016A Cabozantinib hydrochloride Inhibitor / 否
Clinical Phase
生物活性分子 (30)
目录号 产品名 作用方式
纯度 Phase
HY-50751 Linifanib Inhibitor 99.28% Phase 3
HY-16961 Sitravatinib Inhibitor 99.59% Phase 3
HY-50905 Dovitinib Inhibitor 99.94% Phase 3
HY-50867 Lestaurtinib Inhibitor 99.17% Phase 3
HY-10207 Dovitinib lactate Inhibitor 99.62% Phase 3
HY-16961A Sitravatinib malate Inhibitor / Phase 3
HY-B0062 Dovitinib lactate hydrate Inhibitor / Phase 3
HY-135317 Emavusertib Inhibitor 99.96% Phase 2
HY-13024 Rebastinib Inhibitor 99.91% Phase 2
HY-50514 AT9283 Inhibitor 99.70% Phase 2
HY-13034 Gandotinib Inhibitor 99.82% Phase 2
HY-15514 Merestinib Inhibitor 99.99% Phase 2
HY-10206 Amuvatinib Inhibitor 99.47% Phase 2
HY-10987A ENMD-2076 Inhibitor 99.12% Phase 2
HY-100867A TAK-659 hydrochloride Inhibitor 99.91% Phase 2
HY-10202 Tandutinib Inhibitor 99.48% Phase 2
HY-145015 Tuspetinib 99.77% Phase 2
HY-10987 ENMD-2076 Tartrate Inhibitor 99.42% Phase 2
HY-10202A Tandutinib hydrochloride Inhibitor 99.78% Phase 2
HY-15514A Merestinib dihydrochloride Inhibitor 99.36% Phase 2
HY-118304B AKN-028 acetate Inhibitor 99.95% Phase 2
HY-100867 TAK-659 Inhibitor / Phase 2
HY-118304 AKN-028 Inhibitor / Phase 2
HY-10206A Amuvatinib hydrochloride Inhibitor / Phase 2
HY-10339 KW-2449 Inhibitor 99.69% Phase 1
HY-101549 MRX-2843 Inhibitor 99.70% Phase 1
HY-111361 FN-1501 Inhibitor 99.71% Phase 1
HY-B0791 Altiratinib Inhibitor 98.05% Phase 1
HY-139535 Luxeptinib Inhibitor 99.30% Phase 1
HY-13072 Cenisertib Inhibitor 99.64% Phase 1
Pre-clinical Phase
生物活性分子 (111)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13223 Crenolanib Inhibitor 99.68% 是
HY-12067 R406 Inhibitor 98.72% 否
HY-15166 (E/Z)-Zotiraciclib Inhibitor 99.96% 否
HY-12344 UNC2025 Inhibitor 99.83% 否
HY-11108 R406 free base Inhibitor 99.80% 否
HY-10410 TG101209 Inhibitor 99.22% 否
HY-13263 CHIR-124 Inhibitor 98.57% 否
HY-15002 AST 487 Inhibitor 99.42% 否
HY-12333 Denfivontinib Inhibitor ≥98.0% 否
HY-13894 Tyrphostin AG1296 Inhibitor 99.69% 否
HY-12344A UNC2025 hydrochloride Inhibitor 99.87% 否
HY-N0071 Crotonoside Inhibitor 99.64% 否
HY-114323 PROTAC FLT-3 degrader 1 Inhibitor 99.66% 否
HY-12420 JNJ-47117096 hydrochloride Inhibitor 98.01% 否
HY-15889 AMG 925 Inhibitor 98.24% 否
HY-132200 UNC5293 Inhibitor 99.31% 否
HY-153886 Wu-5 Inhibitor 99.34% 否
HY-120758 SEL24-B489 Inhibitor 98.58% 否
HY-18161 CCT241736 Inhibitor 98.09% 否
HY-145723 MAX-40279 Inhibitor 97.10% 否
HY-130247A JAK2/FLT3-IN-1 TFA Inhibitor 99.77% 否
HY-107417 Hypothemycin Inhibitor ≥98.0% 否
HY-18179 AZD2932 Inhibitor 99.04% 否
HY-131906 JAK2-IN-7 Inhibitor 99.15% 否
HY-18744 FLT3-IN-2 Inhibitor 98.38% 否
HY-13493 AC710 Inhibitor 98.56% 否
HY-13907 TCS 359 Inhibitor 99.89% 否
HY-112145 FLT3-IN-3 Inhibitor 99.73% 否
HY-15166B (E/Z)-Zotiraciclib citrate Inhibitor 98.06% 否
HY-13537A BPR1J-097 Hydrochloride Inhibitor 99.20% 否
HY-15166A (E/Z)-Zotiraciclib hydrochloride Inhibitor 99.45% 否
HY-18952A (Z)-SU5614 Inhibitor 98.43% 否
HY-144869 OTS447 Inhibitor 99.83% 否
HY-15003 ATH686 Inhibitor 99.58% 否
HY-13016S Cabozantinib-d6 Inhibitor 98.14% 否
HY-15889A AMG 925 HCl Inhibitor / 否
HY-15198 KG5 Inhibitor 99.79% 否
HY-130247 JAK2/FLT3-IN-1 Inhibitor 99.79% 否
HY-128571 FLT3-IN-4 Inhibitor 98.19% 否
HY-100865 BPR1K871 Inhibitor 98.45% 否
HY-120590 Ruserontinib Inhibitor 99.82% 否
HY-143286A PF15 TFA Degrader 99.72% 否
HY-134481 FLT3-IN-10 Inhibitor 98.80% 否
HY-19897 4SC-203 Inhibitor 99.87% 否
HY-13537 BPR1J-097 Inhibitor / 否
HY-151904 AXL-IN-13 / 否
HY-12432S1 Gilteritinib-d8 Inhibitor ≥98.0% 否
HY-108263 3-Hydroxy Midostaurin Inhibitor 97.02% 否
HY-12960 SKLB4771 Inhibitor 98.08% 否
HY-135317B Emavusertib hydrochloride Inhibitor / 否
HY-128572 FLT3-IN-6 Inhibitor 99.14% 否
HY-145723C MAX-40279 hemiadipate Inhibitor 99.26% 否
HY-145723A MAX-40279 hydrochloride Inhibitor / 否
HY-146749 FLT3/TrKA-IN-1 Inhibitor / 否
HY-15496 E6201 Inhibitor / 否
HY-145723B MAX-40279 hemifumarate Inhibitor 99.56% 否
HY-112475 Flt-3 Inhibitor III Inhibitor / 否
HY-155341 HSK205 Inhibitor / 否
HY-108263S 3-Hydroxy Midostaurin-d5 Inhibitor / 否
HY-110026 GTP-14564 Inhibitor 99.91% 否
HY-139619 LT-850-166 Inhibitor / 否
HY-155112 Antiproliferative agent-30 Inhibitor / 否
HY-143894 FLT3-IN-11 Inhibitor / 否
HY-145904 PDGFRα/FLT3-ITD-IN-3 Inhibitor / 否
HY-153857 PHI-101 Inhibitor 98.97% 否
HY-144711 FLT3/ITD-IN-3 Inhibitor / 否
HY-153473 FLT3-IN-19 Inhibitor 99.19% 否
HY-149539 PLM-101 Inhibitor / 否
HY-145690 HP1328 Inhibitor / 否
HY-10201S2 Sorafenib-13C,d3 Inhibitor / 否
HY-145903 PDGFRα/FLT3-ITD-IN-2 Inhibitor / 否
HY-111249 TTT 3002 Inhibitor / 否
HY-146886 FLT3-IN-15 Inhibitor / 否
HY-143434 FLT3/D835Y-IN-1 Inhibitor / 否
HY-108263B (R)-3-Hydroxy Midostaurin Inhibitor / 否
HY-18949 JI6 Inhibitor / 否
HY-144777 FLT3-IN-14 Inhibitor / 否
HY-148521 PROTAC FLT3/CDK9 degrader-1 Degrader / 否
HY-155594 LT-540-717 Inhibitor / 否
HY-155770 FLT3-IN-20 Inhibitor / 否
HY-144710 FLT3/ITD-IN-2 Inhibitor / 否
HY-151945 TRK II-IN-1 Inhibitor / 否
HY-143895 FLT3-IN-12 Inhibitor / 否
HY-150582 c-Met-IN-14 Inhibitor / 否
HY-145691 HP1142 Inhibitor / 否
HY-157213 LWY713 Degrader / 否
HY-108263A (S)-3-Hydroxy Midostaurin Inhibitor / 否
HY-149474 HDAC-IN-63 Inhibitor / 否
HY-156410 FLT3-IN-23 Inhibitor / 否
HY-50905S Dovitinib-d8 Inhibitor / 否
HY-144709 FLT3/ITD-IN-1 Inhibitor / 否
HY-143278 FLT3-IN-13 Inhibitor / 否
HY-103464 5'-Fluoroindirubinoxime Inhibitor ≥98.0% 否
HY-115906 K783-0308 Inhibitor / 否
HY-151961 RSH-7 Inhibitor 99.07% 否
HY-148036 FLT3-IN-16 Inhibitor 98.98% 否
HY-148070 FLT3-IN-17 Inhibitor 99.56% 否
HY-145902 PDGFRα/FLT3-ITD-IN-1 Inhibitor / 否
HY-155226 FLT3-IN-21 Inhibitor / 否
HY-146680 FLT3/ITD-IN-4 Inhibitor / 否
HY-143286 PF15 Inhibitor / 否
HY-13016S1 Cabozantinib-d4 Inhibitor / 否
HY-148522 FLT3-IN-18 Inhibitor / 否
HY-115904 FLT3/CDK4-IN-1 Inhibitor / 否
HY-155302 FLT3-IN-22 Inhibitor / 否
HY-15519 LBW242 Inhibitor / 否
HY-124502 UNC4203 Inhibitor / 否
HY-10201S1 Sorafenib-d4 Inhibitor / 否
HY-15163 Zotiraciclib Inhibitor / 否
HY-10058 AT9283 lactic acid Inhibitor / 否
HY-111545 BSc5371 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens FLT3 NCBI NCBI:2322
Macaca fascicularis FLT3 NCBI NCBI:102144988
Mus musculus FLT3 NCBI NCBI:14255
Susscrofa domestica FLT3 NCBI
Rattus norvegicus FLT3 NCBI NCBI:140635
Macaca mulatta FLT3 NCBI NCBI:721712