2. Gene
  3. JAK3 - Janus kinase 3 Gene

JAK3 - Janus kinase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：两面神激酶 3

种属: Sus scrofa

基因 ID: 100518649 | 基因类型: protein coding

关于 JAK3

Primary_assembly 2: 59,905,919-59,926,495 forward strand.Sscrofa11.1:CM000813.5

This gene has 1 transcript (splice variant), 103 orthologues and 32 paralogues. Broad expression in spleen (RPKM 36.5), lung (RPKM 13.2) and 6 other tissues.

JAK3 基因产物(5)

mRNA Protein Name
XM_005654907.3 XP_005654964.1 tyrosine-protein kinase JAK3 isoform X1
XM_021083532.1 XP_020939191.1 tyrosine-protein kinase JAK3 isoform X2
XM_003123500.4 XP_003123548.1 tyrosine-protein kinase JAK3 isoform X1
XM_013987479.2 XP_013842933.1 tyrosine-protein kinase JAK3 isoform X1
XM_013987480.2 XP_013842934.1 tyrosine-protein kinase JAK3 isoform X1

JAK3 蛋白结构

FERM_F1

FERM_F1: cl39717 (40 - 111)

FERM_F2

FERM_F2: cl39028 (125 - 244)

PH-like

PH-like: cl17171 (249 - 360)

SH2

SH2: cl15255 (360 - 456)

PKc_like

PKc_like: cl21453 (519 - 776)

PTKc_Jak3_rpt2

PTKc_Jak3_rpt2: cd05081 (815 - 1097)

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  • 1103 a.a.
蛋白主名 其他名称

tyrosine-protein kinase JAK3

相关产品

Approval
生物活性分子 (19)
目录号 产品名 作用方式
纯度 是否罕见病
HY-50856 Ruxolitinib Inhibitor 99.99% 是
HY-40354 Tofacitinib Inhibitor 99.99% 是
HY-15315 Baricitinib Inhibitor 99.97% 是
HY-19569 Upadacitinib Inhibitor 99.97% 是
HY-50858 Ruxolitinib phosphate Inhibitor 99.98% 是
HY-40354A Tofacitinib citrate Inhibitor 99.98% 是
HY-16379 Pacritinib Inhibitor 99.93% 是
HY-18300 Filgotinib Inhibitor 99.68% 是
HY-19568 Peficitinib Inhibitor 99.43% 是
HY-15315A Baricitinib phosphate Inhibitor 99.91% 是
HY-109053 Delgocitinib Inhibitor 99.87% 否
HY-13577A Oclacitinib maleate Inhibitor 99.63% 否
HY-13577 Oclacitinib Inhibitor 99.23% 否
HY-19569A Upadacitinib tartrate tetrahydrate Inhibitor / 否
HY-19568A Peficitinib hydrobromide Inhibitor / 否
HY-16379A Pacritinib hydrochloride Inhibitor / 否
HY-18300A Filgotinib maleate Inhibitor / 否
HY-19568B Peficitinib hydrochloride Inhibitor / 否
HY-50859 Ruxolitinib sulfate Inhibitor / 否
Clinical Phase
生物活性分子 (18)
目录号 产品名 作用方式
纯度 Phase
HY-100754 Ritlecitinib Inhibitor 99.98% Phase 3
HY-10961 Momelotinib Inhibitor 98.93% Phase 3
HY-15999 Cerdulatinib Inhibitor 98.96% Phase 3
HY-12469 Decernotinib Inhibitor 99.67% Phase 3
HY-10962 Momelotinib sulfate Inhibitor 98.06% Phase 3
HY-15999A Cerdulatinib hydrochloride Inhibitor 99.89% Phase 3
HY-112724 Ivarmacitinib Inhibitor 99.82% Phase 3
HY-10963 Momelotinib Mesylate Inhibitor / Phase 3
HY-50514 AT9283 Inhibitor 99.70% Phase 2
HY-13034 Gandotinib Inhibitor 99.82% Phase 2
HY-112708A Brepocitinib P-Tosylate Inhibitor 99.86% Phase 2
HY-15270 BMS-911543 Inhibitor 98.53% Phase 2
HY-19631A Ilginatinib Inhibitor 99.53% Phase 2
HY-19631B Ilginatinib hydrochloride Inhibitor ≥98.0% Phase 2
HY-112708 Brepocitinib Inhibitor 98.64% Phase 2
HY-19631 Ilginatinib maleate Inhibitor 99.87% Phase 2
HY-13775 XL019 Inhibitor ≥98.0% Phase 1
HY-101024 PF-06263276 Inhibitor 99.38% Phase 1
Pre-clinical Phase
生物活性分子 (58)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14435 Pyridone 6 Inhibitor 98.84% 否
HY-10410 TG101209 Inhibitor 99.22% 否
HY-10411 AZ960 Inhibitor 97.15% 否
HY-15343 CEP-33779 Inhibitor 98.68% 否
HY-15508 JANEX-1 Inhibitor 99.84% 否
HY-100895 SAR-20347 Inhibitor 97.12% 否
HY-131140 BD750 Inhibitor 99.10% 否
HY-13895 WHI-P154 Inhibitor 99.39% 否
HY-12589 ZM39923 hydrochloride Inhibitor 98.19% 否
HY-145696 SJ10542 Inhibitor 99.92% 否
HY-101976 JAK3-IN-6 Inhibitor 98.07% 否
HY-102046 FM-381 Inhibitor 99.58% 否
HY-108264 TCS 21311 Inhibitor 99.18% 否
HY-14722A NVP-BSK805 dihydrochloride Inhibitor 99.36% 否
HY-120469 2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide Inhibitor 98.78% 否
HY-14722 NVP-BSK805 Inhibitor 99.89% 否
HY-150023 BI-1622 Inhibitor 98.97% 否
HY-130247A JAK2/FLT3-IN-1 TFA Inhibitor 99.77% 否
HY-126141 JAK/HDAC-IN-1 Inhibitor 98.53% 否
HY-131906 JAK2-IN-7 Inhibitor 99.15% 否
HY-139423 JAK1-IN-8 Inhibitor ≥95.0% 否
HY-151262 JAK-IN-23 Inhibitor 98.90% 否
HY-11067 WHI-P97 Inhibitor 99.70% 否
HY-13961 GLPG0634 analog Inhibitor 98.58% 否
HY-19544 JAK3-IN-1 Inhibitor 99.23% 否
HY-100754B (2R,5S)-Ritlecitinib Inhibitor 98.83% 否
HY-130247 JAK2/FLT3-IN-1 Inhibitor 99.79% 否
HY-119935 JAK3 covalent inhibitor-1 Inhibitor / 否
HY-152080 TUL01101 Inhibitor / 否
HY-143444 JAK-IN-20 Inhibitor / 否
HY-151256 JAK-2/3-IN-2 Inhibitor / 否
HY-133747 JAK3-IN-9 Inhibitor / 否
HY-10652 JAK-2/3-IN-1 Inhibitor / 否
HY-147742 Thi-DPPY Inhibitor / 否
HY-150720 TYK2-IN-12 Inhibitor / 否
HY-157121 JAK-IN-34 Inhibitor / 否
HY-149283 JAK/HDAC-IN-2 Inhibitor / 否
HY-151259 TK4b Inhibitor / 否
HY-18949 JI6 Inhibitor / 否
HY-147741 DPPY Inhibitor / 否
HY-123099 MS-1020 Inhibitor / 否
HY-100849 JAK 3i Inhibitor / 否
HY-151285 JAK-2/3-IN-3 Inhibitor / 否
HY-151258 TK4g Inhibitor / 否
HY-149296 JAK1-IN-12 Inhibitor / 否
HY-146727 JAK3-IN-11 Inhibitor / 否
HY-108342 PF-00956980 Inhibitor / 否
HY-131014 FM-479 / 否
HY-153440 JAK-IN-25 Inhibitor 98.44% 否
HY-143885 JAK1/TYK2-IN-3 Inhibitor / 否
HY-154994 JAK-IN-30 Inhibitor / 否
HY-147975 JAK3-IN-12 Inhibitor / 否
HY-155951 JAK3-IN-14 Inhibitor 99.32% 否
HY-147754 JAK3/BTK-IN-6 Inhibitor / 否
HY-10058 AT9283 lactic acid Inhibitor / 否
HY-12589A ZM39923 Inhibitor / 否
HY-111750 JAK-IN-3 Inhibitor 98.92% 否
HY-U00390 JAK3-IN-7 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens JAK3 NCBI NCBI:3718