2. Gene
  3. HIPK3 - homeodomain interacting protein kinase 3 Gene

HIPK3 - homeodomain interacting protein kinase 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 直系同源

中文名称：同源结构域相互作用蛋白激酶 3

种属: Homo sapiens

同用名: PKY; YAK1; DYRK6; FIST3

基因 ID: 10114 | 基因类型: protein coding

关于 HIPK3

Cytogenetic location: 11p13 Genomic coordinates (GRCh38): 11:33,256,672-33,357,023 (from NCBI)

This gene has 6 transcripts (splice variants), 273 orthologues and 12 paralogues. Ubiquitous expression in fat (RPKM 29.7), gall bladder (RPKM 21.4) and 25 other tissues.

功能概要

启用蛋白质丝氨酸/苏氨酸激酶活性。参与 mRNA 转录；细胞凋亡过程的负调控；和蛋白质磷酸化。位于胞质溶胶中；核体；和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity. Involved in mRNA transcription; negative regulation of apoptotic process; and protein phosphorylation. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

HIPK3 基因产物(4)

mRNA Protein Name
NM_001048200.3 NP_001041665.1 homeodomain-interacting protein kinase 3 isoform 2
NM_001278162.2 NP_001265091.1 homeodomain-interacting protein kinase 3 isoform 2
NM_001278163.2 NP_001265092.1 homeodomain-interacting protein kinase 3 isoform 2
NM_005734.5 NP_005725.3 homeodomain-interacting protein kinase 3 isoform 1

HIPK3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (197 - 525)

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  • 1215 a.a.
蛋白主名 其他名称

homeodomain-interacting protein kinase 3

ANPK

关联疾病

疾病名称 别名
Huntington Disease

Huntington'S Disease

Huntington Chorea

Huntington'S Chorea

HD

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris HIPK3 VGNC VGNC:41695
Mus musculus HIPK3 MGD MGI:1314882
Felis catus HIPK3 VGNC VGNC:67574
Bos taurus HIPK3 VGNC VGNC:29860
Macaca mulatta HIPK3 VGNC VGNC:73472
Rattus norvegicus HIPK3 RGD RGD:619884
Others HIPK3 NCBI