2. Gene
  3. JAK1 - Janus kinase 1 Gene

JAK1 - Janus kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：两面神激酶 1

种属: Macaca fascicularis

基因 ID: 102123983 | 基因类型: protein coding

关于 JAK1

Primary_assembly 1: 159,149,049-159,279,381 forward strand.Macaca_fascicularis_6.0:CM021939.1

This gene has 3 transcripts (splice variants), 238 orthologues and 30 paralogues.

JAK1 基因产物(1)

mRNA Protein Name
XM_005543157.3 XP_005543214.1 tyrosine-protein kinase JAK1

JAK1 蛋白结构

FERM_F1

FERM_F1: cl39717 (35 - 128)

FERM_F2

FERM_F2: pfam18377 (146 - 276)

FERM_C_JAK1

FERM_C_JAK1: cd13332 (281 - 425)

SH2

SH2: cl15255 (425 - 526)

PTK_Jak1_rpt1

PTK_Jak1_rpt1: cd05077 (582 - 845)

PTKc_Jak1_rpt2

PTKc_Jak1_rpt2: cd05079 (869 - 1152)

  • 0
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  • 1000
  • 1154 a.a.
蛋白主名 其他名称

tyrosine-protein kinase JAK1

相关产品

Approval
生物活性分子 (21)
目录号 产品名 作用方式
纯度 是否罕见病
HY-50856 Ruxolitinib Inhibitor 99.99% 是
HY-40354 Tofacitinib Inhibitor 99.99% 是
HY-15315 Baricitinib Inhibitor 99.97% 是
HY-117287 Deucravacitinib Inhibitor 99.87% 是
HY-19569 Upadacitinib Inhibitor 99.97% 是
HY-50858 Ruxolitinib phosphate Inhibitor 99.98% 是
HY-40354A Tofacitinib citrate Inhibitor 99.98% 是
HY-16379 Pacritinib Inhibitor 99.93% 是
HY-18300 Filgotinib Inhibitor 99.68% 是
HY-19568 Peficitinib Inhibitor 99.43% 是
HY-107429 Abrocitinib Inhibitor 99.26% 否
HY-15315A Baricitinib phosphate Inhibitor 99.91% 是
HY-109053 Delgocitinib Inhibitor 99.87% 否
HY-13577A Oclacitinib maleate Inhibitor 99.63% 否
HY-13577 Oclacitinib Inhibitor 99.23% 否
HY-19568A Peficitinib hydrobromide Inhibitor / 否
HY-19569A Upadacitinib tartrate tetrahydrate Inhibitor / 否
HY-16379A Pacritinib hydrochloride Inhibitor / 否
HY-18300A Filgotinib maleate Inhibitor / 否
HY-19568B Peficitinib hydrochloride Inhibitor / 否
HY-50859 Ruxolitinib sulfate Inhibitor / 否
Clinical Phase
生物活性分子 (21)
目录号 产品名 作用方式
纯度 Phase
HY-10961 Momelotinib Inhibitor 98.93% Phase 3
HY-16997 Itacitinib Inhibitor 99.97% Phase 3
HY-15999 Cerdulatinib Inhibitor 98.96% Phase 3
HY-12469 Decernotinib Inhibitor 99.67% Phase 3
HY-10962 Momelotinib sulfate Inhibitor 98.06% Phase 3
HY-15999A Cerdulatinib hydrochloride Inhibitor 99.89% Phase 3
HY-112724 Ivarmacitinib Inhibitor 99.82% Phase 3
HY-16997A Itacitinib adipate Inhibitor 99.18% Phase 3
HY-50856S Deuruxolitinib Inhibitor / Phase 3
HY-10963 Momelotinib Mesylate Inhibitor / Phase 3
HY-112708A Brepocitinib P-Tosylate Inhibitor 99.86% Phase 2
HY-15270 BMS-911543 Inhibitor 98.53% Phase 2
HY-107361 Golidocitinib Inhibitor 99.75% Phase 2
HY-19631A Ilginatinib Inhibitor 99.53% Phase 2
HY-16755 Solcitinib Inhibitor 99.73% Phase 2
HY-19631B Ilginatinib hydrochloride Inhibitor ≥98.0% Phase 2
HY-112708 Brepocitinib Inhibitor 98.64% Phase 2
HY-19631 Ilginatinib maleate Inhibitor 99.87% Phase 2
HY-10193 AZD-1480 Inhibitor 99.56% Phase 1
HY-126294 Londamocitinib Inhibitor 98.98% Phase 1
HY-101024 PF-06263276 Inhibitor 99.38% Phase 1
Pre-clinical Phase
生物活性分子 (43)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W063968 RO8191 Activator ≥99.0% 否
HY-14435 Pyridone 6 Inhibitor 98.84% 否
HY-100895 SAR-20347 Inhibitor 97.12% 否
HY-12589 ZM39923 hydrochloride Inhibitor 98.19% 否
HY-151385 VVD-118313 Inhibitor 99.75% 否
HY-108264 TCS 21311 Inhibitor 99.18% 否
HY-14722A NVP-BSK805 dihydrochloride Inhibitor 99.36% 否
HY-120469 2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide Inhibitor 98.78% 否
HY-14722 NVP-BSK805 Inhibitor 99.89% 否
HY-130247A JAK2/FLT3-IN-1 TFA Inhibitor 99.77% 否
HY-126141 JAK/HDAC-IN-1 Inhibitor 98.53% 否
HY-131906 JAK2-IN-7 Inhibitor 99.15% 否
HY-139423 JAK1-IN-8 Inhibitor ≥95.0% 否
HY-151262 JAK-IN-23 Inhibitor 98.90% 否
HY-13961 GLPG0634 analog Inhibitor 98.58% 否
HY-19544 JAK3-IN-1 Inhibitor 99.23% 否
HY-130247 JAK2/FLT3-IN-1 Inhibitor 99.79% 否
HY-151385A (R,R)-VVD-118313 Inhibitor 99.54% 否
HY-W394903 GS-829845 Inhibitor 99.91% 否
HY-14722C NVP-BSK805 trihydrochloride Inhibitor / 否
HY-156409 ABBV-712 Inhibitor / 否
HY-152080 TUL01101 Inhibitor / 否
HY-143444 JAK-IN-20 Inhibitor / 否
HY-139649 Ten01 Inhibitor / 否
HY-100849 JAK 3i Inhibitor / 否
HY-108342 PF-00956980 Inhibitor / 否
HY-150720 TYK2-IN-12 Inhibitor / 否
HY-157121 JAK-IN-34 Inhibitor / 否
HY-149296 JAK1-IN-12 Inhibitor / 否
HY-15814 HG-7-85-01 Inhibitor / 否
HY-153566 JAK1-IN-10 Inhibitor / 否
HY-143885 JAK1/TYK2-IN-3 Inhibitor / 否
HY-149283 JAK/HDAC-IN-2 Inhibitor / 否
HY-153440 JAK-IN-25 Inhibitor 98.44% 否
HY-144440 JAK1-IN-9 Inhibitor / 否
HY-147975 JAK3-IN-12 Inhibitor / 否
HY-146727 JAK3-IN-11 Inhibitor / 否
HY-147754 JAK3/BTK-IN-6 Inhibitor / 否
HY-148060 JAK-IN-21 Inhibitor / 否
HY-154994 JAK-IN-30 Inhibitor / 否
HY-12589A ZM39923 Inhibitor / 否
HY-111750 JAK-IN-3 Inhibitor 98.92% 否
HY-116505 JAK1-IN-4 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens JAK1 NCBI NCBI:3716