1. Gene
  2. Phb2 - prohibitin 2 Gene

Phb2 - prohibitin 2 Gene

种属: Rattus norvegicus

同用名: Bap; Bap37; Bap-37; Bcap27; Bcap37

基因 ID: 114766 | 基因类型: protein coding

关于 Phb2

功能概要

Predicted to enable several functions, including protein C-terminus binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in several processes, including cellular response to hypoxia; cellular response to retinoic acid; and negative regulation of apoptotic process. Located in mitochondrion and nucleus. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic density. Colocalizes with axon. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, Apr 2022]

Phb2 基因产物(1)

mRNA Protein Name
NM_001013035.1 NP_001013053.1 prohibitin-2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
25031298 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
25031298 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
24566151 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
23622064 RGD
located in axon IDA
IDA: 通过直接分析推断
23568660 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
17623647 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17623647 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
19116139 RGD
is active in postsynaptic density EXP
EXP: 通过实验结果推断
17623647 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
17623647 RGD
is active in presynaptic active zone EXP
EXP: 通过实验结果推断
23622064 RGD
is active in presynaptic active zone IDA
IDA: 通过直接分析推断
23622064 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prohibitin-2

B-cell receptor associated protein 37

B-cell receptor-associated protein BAP37

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phb2 NCBI NCBI:11331
Macaca fascicularis Phb2 NCBI NCBI:102136314
Mus musculus Phb2 NCBI NCBI:12034