1. Gene
  2. Dmbt1 - deleted in malignant brain tumors 1 Gene

Dmbt1 - deleted in malignant brain tumors 1 Gene

种属: Mus musculus

同用名: CRP; p80; Crpd; DBMT1; gp300; CRP-[a]; CRP-[b]

基因 ID: 12945 | 基因类型: protein coding

关于 Dmbt1

功能概要

Enables zymogen binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Acts upstream of or within inner cell mass cell proliferation; positive regulation of epithelial cell differentiation; and response to bacterium. Located in extracellular matrix and zymogen granule membrane. Is extrinsic component of membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; retina; and spleen. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human DMBT1 (deleted in malignant brain tumors 1). [provided by Alliance of Genome Resources, Apr 2022]

Dmbt1 基因产物(2)

mRNA Protein Name
NM_001347632.2 NP_001334561.1 deleted in malignant brain tumors 1 protein isoform 1 precursor
NM_007769.3 NP_031795.2 deleted in malignant brain tumors 1 protein isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12884308 MGI
enables zymogen binding IDA
IDA: 通过直接分析推断
15292166 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
9247472 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
15452149 MGI
located in zymogen granule membrane IDA
IDA: 通过直接分析推断
7876332 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

deleted in malignant brain tumors 1 protein

apactin

crp-ductin

deleted in malignant brain tumors 1 pseudogene

ebnerin

glycoprotein 300

hensin

mucin-like glycoprotein

muclin

vomeroglandin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dmbt1 NCBI NCBI:1755