2. Gene
  3. Ncl - nucleolin Gene

Ncl - nucleolin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C23; Nucl; D0Nds28; D1Nds28; B530004O11Rik

基因 ID: 17975 | 基因类型: protein coding

关于 Ncl

功能概要

Enables RNA binding activity. Acts upstream of or within cellular response to epidermal growth factor stimulus; cellular response to leukemia inhibitory factor; and positive regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. Is expressed in several structures, including 1st branchial arch mandibular component; blastocyst; central nervous system; early embryo; and tooth. Orthologous to human NCL (nucleolin). [provided by Alliance of Genome Resources, Apr 2022]

Ncl 基因产物(1)

mRNA Protein Name
NM_010880.3 NP_035010.3 nucleolin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PH domain binding IPI
IPI: 通过物理相互作用推断
9813005 MGI
enables RNA binding IDA
IDA: 通过直接分析推断
17971306 MGI
enables insulin receptor substrate binding IPI
IPI: 通过物理相互作用推断
9813005 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10567518 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to epidermal growth factor stimulus IDA
IDA: 通过直接分析推断
8702723 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
9813005 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
24530304 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
9813005 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
2100262 MGI
located in nucleoplasm IDA
IDA: 通过直接分析推断
17971306 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9102301 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nucleolin

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-174346 Skp2-IN-4 Inhibitor / 否
HY-12645 NCL1 Inhibitor / 否
HY-178048 Neuroprotective agent 13 Activator / 否
HY-178052 Neuroprotective agent 14 Activator / 否
HY-RS03886 DNAJC5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09086 NCL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P5551 TLN-58 Inhibitor / 否
HY-RS17936 Ncl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24407 Ncl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncl NCBI NCBI:4691
Macaca mulatta Ncl NCBI NCBI:720965
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