2. Gene
  3. P4ha1 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide Gene

P4ha1 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: P4ha

基因 ID: 18451 | 基因类型: protein coding

关于 P4ha1

功能概要

Enables procollagen-proline 4-dioxygenase activity. Acts upstream of or within Collagen fibril organization and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Part of procollagen-proline 4-dioxygenase complex. Is expressed in several structures, including genitourinary system; jaw; limb; sensory organ; and skeleton. Orthologous to human P4HA1 (prolyl 4-hydroxylase subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

P4ha1 基因产物(3)

mRNA Protein Name
NM_001316370.1 NP_001303299.1 prolyl 4-hydroxylase subunit alpha-1 isoform 1 precursor
NM_001316371.1 NP_001303300.1 prolyl 4-hydroxylase subunit alpha-1 isoform 2 precursor
NM_011030.2 NP_035160.1 prolyl 4-hydroxylase subunit alpha-1 isoform 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables procollagen-proline 4-dioxygenase activity IDA
IDA: 通过直接分析推断
7753822 MGI
enables procollagen-proline 4-dioxygenase activity IMP
IMP: 通过突变表型推断
17135260 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
17135260 MGI
acts upstream of or within peptidyl-proline hydroxylation to 4-hydroxy-L-proline IDA
IDA: 通过直接分析推断
7753822 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of procollagen-proline 4-dioxygenase complex IDA
IDA: 通过直接分析推断
7753822 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolyl 4-hydroxylase subunit alpha-1

4-PH alpha-1

procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121172 1,4-DPCA Inhibitor 98.36% 否
HY-RS09942 P4HA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16973 P4ha1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23416 P4ha1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P4ha1 NCBI NCBI:5033
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