2. Gene
  3. Ryk - receptor-like tyrosine kinase Gene

Ryk - receptor-like tyrosine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vik; ERK-3

基因 ID: 20187 | 基因类型: protein coding

关于 Ryk

功能概要

Enables Wnt-activated receptor activity; Wnt-protein binding activity; and Frizzled binding activity. Involved in nervous system development. Acts upstream of or within generation of neurons; negative chemotaxis; and skeletal system morphogenesis. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human RYK (receptor like tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Ryk 基因产物(3)

mRNA Protein Name
NM_001042607.1 NP_001036072.1 tyrosine-protein kinase RYK isoform 2 precursor
NM_001284258.1 NP_001271187.1 tyrosine-protein kinase RYK isoform 3
NM_013649.3 NP_038677.3 tyrosine-protein kinase RYK isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt receptor activity IPI
IPI: 通过物理相互作用推断
15454084 MGI
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
15454084 MGI
enables frizzled binding IPI
IPI: 通过物理相互作用推断
15454084 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10932185 MGI
NOT enables protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
1334548 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Wnt signaling pathway IDA
IDA: 通过直接分析推断
15454084 MGI
acts upstream of or within Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
16723543 MGI
acts upstream of axon extension involved in axon guidance IGI
IGI: 通过遗传相互作用推断
16723543 MGI
involved in axon guidance IDA
IDA: 通过直接分析推断
16116452 MGI
involved in axon guidance IMP
IMP: 通过突变表型推断
16723543 MGI
acts upstream of or within axonogenesis IGI
IGI: 通过遗传相互作用推断
15454084 MGI
involved in chemorepulsion of dopaminergic neuron axon IGI
IGI: 通过遗传相互作用推断
23517308 MGI
acts upstream of or within commissural neuron axon guidance IMP
IMP: 通过突变表型推断
16723543 MGI
involved in corpus callosum development IMP
IMP: 通过突变表型推断
16723543 MGI
involved in midbrain dopaminergic neuron differentiation IMP
IMP: 通过突变表型推断
23517308 MGI
acts upstream of or within negative chemotaxis IGI
IGI: 通过遗传相互作用推断
16723543 MGI
acts upstream of or within negative regulation of axon extension involved in axon guidance IGI
IGI: 通过遗传相互作用推断
16723543 MGI
involved in neuron differentiation IDA
IDA: 通过直接分析推断
19000841 MGI
involved in neuron projection development IMP
IMP: 通过突变表型推断
15454084 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: 通过突变表型推断
10932185 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19000841 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
34407949 MGI
located in membrane IDA
IDA: 通过直接分析推断
8394755 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19000841 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
7822791 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
34407949 MGI
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
34407949 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase RYK

NYK-R

growth factor receptor

kinase VIK

met-related kinase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12367 RYK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18743 Ryk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25230 Ryk Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ryk NCBI NCBI:6259
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