2. Gene
  3. Nptn - neuroplastin Gene

Nptn - neuroplastin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SDR-1; Sdfr1

基因 ID: 20320 | 基因类型: protein coding

关于 Nptn

功能概要

Predicted to enable cell-cell adhesion mediator activity; transmembrane transporter binding activity; and type 1 Fibroblast Growth Factor receptor binding activity. Involved in cellular calcium ion homeostasis and negative regulation of cytokine production. Acts upstream of or within excitatory synapse assembly; modulation of chemical synaptic transmission; and regulation of receptor localization to synapse. Located in dendrite and immunological synapse. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; nervous system; and respiratory system. Orthologous to human NPTN (neuroplastin). [provided by Alliance of Genome Resources, Apr 2022]

Nptn 基因产物(4)

mRNA Protein Name
NM_001293673.2 NP_001280602.1 neuroplastin isoform 2 precursor
NM_001357751.2 NP_001344680.1 neuroplastin isoform 3 precursor
NM_001406062.1 NP_001392991.1 neuroplastin isoform 4 precursor
NM_009145.3 NP_033171.2 neuroplastin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28827723 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within excitatory synapse assembly IMP
IMP: 通过突变表型推断
24554721 MGI
involved in intracellular calcium ion homeostasis IMP
IMP: 通过突变表型推断
28827723 MGI
acts upstream of or within modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
24554721 MGI
involved in negative regulation of cytokine production IMP
IMP: 通过突变表型推断
28827723 MGI
acts upstream of or within regulation of receptor localization to synapse IMP
IMP: 通过突变表型推断
24554721 MGI
acts upstream of or within synapse organization IMP
IMP: 通过突变表型推断
24554721 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in immunological synapse IDA
IDA: 通过直接分析推断
28827723 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuroplastin

stromal cell derived factor receptor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09504 NPTN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19925 Nptn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26427 Nptn Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nptn NCBI NCBI:27020
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