2. Gene
  3. Tank - TRAF family member-associated Nf-kappa B activator Gene

Tank - TRAF family member-associated Nf-kappa B activator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: I-TRAF; E430026L09Rik

基因 ID: 21353 | 基因类型: protein coding

关于 Tank

功能概要

Predicted to enable Deubiquitinase activator activity and ubiquitin protein Ligase binding activity. Predicted to contribute to thiol-dependent Deubiquitinase. Acts upstream of or within I-kappaB kinase/NF-kappaB signaling. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human TANK (TRAF family member associated NFKB activator). [provided by Alliance of Genome Resources, Apr 2022]

Tank 基因产物(7)

mRNA Protein Name
NM_001164071.1 NP_001157543.1 TRAF family member-associated NF-kappa-B activator isoform 1
NM_001164072.1 NP_001157544.1 TRAF family member-associated NF-kappa-B activator isoform 2
NM_001355267.1 NP_001342196.1 TRAF family member-associated NF-kappa-B activator isoform 1
NM_001355268.1 NP_001342197.1 TRAF family member-associated NF-kappa-B activator isoform 4
NM_001374667.1 NP_001361596.1 TRAF family member-associated NF-kappa-B activator isoform 5
NM_001378922.1 NP_001365851.1 TRAF family member-associated NF-kappa-B activator isoform 6
NM_011529.2 NP_035659.1 TRAF family member-associated NF-kappa-B activator isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular function inhibitor activity IDA
IDA: 通过直接分析推断
8710854 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10581243 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of tumor necrosis factor-mediated signaling pathway IDA
IDA: 通过直接分析推断
8710854 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TRAF family member-associated NF-kappa-B activator

TRAF-interacting protein

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111941 GSK8612 Inhibitor 99.62% 否
HY-152237 TBK1-IN-1 Inhibitor 99.63% 否
HY-112557 PROTAC TBK1 degrader-2 Inhibitor 98.20% 否
HY-117700 TNKS-IN-2 Inhibitor / 否
HY-RS14197 TANK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18372 Tank Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24851 Tank Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tank NCBI NCBI:10010
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