2. Gene
  3. Trpc6 - transient receptor potential cation channel, subfamily C, member 6 Gene

Trpc6 - transient receptor potential cation channel, subfamily C, member 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TRP-6; Trrp6; mtrp6; LLHWJM002; LLHWJM003; LLHWJM004

基因 ID: 22068 | 基因类型: protein coding

关于 Trpc6

功能概要

Enables store-operated Calcium Channel activity. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Located in plasma membrane and slit diaphragm. Is expressed in several structures, including gut; limb; liver; nervous system; and reproductive system. Used to study focal segmental glomerulosclerosis 2. Human ortholog(s) of this gene implicated in chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Orthologous to human TRPC6 (transient receptor potential cation channel subfamily C member 6). [provided by Alliance of Genome Resources, Apr 2022]

Trpc6 基因产物(3)

mRNA Protein Name
NM_001282086.1 NP_001269015.1 short transient receptor potential channel 6 isoform 2
NM_001282087.1 NP_001269016.1 short transient receptor potential channel 6 isoform 3
NM_013838.2 NP_038866.2 short transient receptor potential channel 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoatomic ion channel activity IDA
IDA: 通过直接分析推断
15194687 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15924139 MGI
enables store-operated calcium channel activity IDA
IDA: 通过直接分析推断
8646775 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
9368034 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
15924139 MGI
located in slit diaphragm IDA
IDA: 通过直接分析推断
15924139 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

short transient receptor potential channel 6

calcium entry channel

transient receptor protein 6

相关产品

Pre-clinical Phase
生物活性分子 (31)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111925 BI-749327 Antagonist 99.91% 否
HY-111098 GSK1702934A Agonist 99.11% 否
HY-116330A Hyperforin dicyclohexylammonium salt 99.48% 否
HY-101507 Zerencotrep Inhibitor 99.47% 否
HY-12949 ML204 Inhibitor 98.45% 否
HY-15699 SAR7334 Inhibitor 99.21% 否
HY-108457 9-Phenanthrol Inhibitor 99.61% 否
HY-122051 AC1903 Inhibitor 99.80% 否
HY-15699A SAR7334 hydrochloride Inhibitor 98.0% 否
HY-101795 Larixyl acetate Inhibitor 99.46% 否
HY-12949A ML204 hydrochloride Inhibitor 99.74% 否
HY-136190 TRPC6-PAM-C20 Agonist 99.78% 否
HY-N10756 Hyp9 Agonist 99.90% 否
HY-148129 Apecotrep Inhibitor 99.17% 否
HY-W744699 Larixol Inhibitor 95.52% 否
HY-133012 GFB-8438 Inhibitor 99.74% 否
HY-111527 PPZ2 99.92% 否
HY-101547 TRPC6-IN-1 Inhibitor 99.71% 否
HY-116330 Hyperforin / 否
HY-120818 TRPC3/6-IN-3 / 否
HY-121519 GSK2332255B Antagonist / 否
HY-145151 TRPC6-IN-2 / 否
HY-147357 TRPC3/6-IN-1 Inhibitor / 否
HY-153455 TRPC3/6-IN-2 Inhibitor / 否
HY-172600 TRPC6 antagonist-1 Antagonist / 否
HY-RS15109 TRPC6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W707161 4-Methyl-2-(1-piperidinyl)-quinoline-d10 / 否
HY-W745090 Isomaltulose monohydrate / 否
HY-RS16595 Trpc6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23029 Trpc6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-112298 DS88790512 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpc6 NCBI NCBI:7225
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