1. Gene
  2. Cplx3 - complexin 3 Gene

Cplx3 - complexin 3 Gene

种属: Mus musculus

同用名: ERGL; CpxIII; Lamn1l; Lman1l; ERGIC-53L

基因 ID: 235415 | 基因类型: protein coding

关于 Cplx3

功能概要

Enables SNARE binding activity and neurotransmitter transmembrane transporter activity. Involved in Insulin secretion; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle exocytosis. Acts upstream of or within regulation of neurotransmitter secretion. Located in cytosol; photoreceptor ribbon synapse; and plasma membrane. Is anchored component of presynaptic active zone membrane and anchored component of synaptic vesicle membrane. Is expressed in cerebral cortex and cortical layer V. Orthologous to human CPLX3 (complexin 3). [provided by Alliance of Genome Resources, Apr 2022]

Cplx3 基因产物(1)

mRNA Protein Name
NM_146223.3 NP_666335.1 complexin-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNARE binding IDA
IDA: 通过直接分析推断
15911881 MGI
enables neurotransmitter transmembrane transporter activity IMP
IMP: 通过突变表型推断
15911881 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in insulin secretion IMP
IMP: 通过突变表型推断
15911881 MGI
acts upstream of or within regulation of neurotransmitter secretion IDA
IDA: 通过直接分析推断
15911881 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IDA
IDA: 通过直接分析推断
27239031 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IMP
IMP: 通过突变表型推断
27239031 MGI
involved in synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
15911881 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
15911881 MGI
located in membrane IDA
IDA: 通过直接分析推断
15911881 MGI
NOT located in nucleus IDA
IDA: 通过直接分析推断
15911881 MGI
is active in photoreceptor ribbon synapse IDA
IDA: 通过直接分析推断
27239031 MGI
is active in photoreceptor ribbon synapse IMP
IMP: 通过突变表型推断
27239031 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15911881 MGI
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
15911881 MGI
is active in presynaptic active zone membrane IEP
IEP: 通过表达模式推断
15911881 MGI
is active in presynaptic active zone membrane IMP
IMP: 通过突变表型推断
15911881 MGI
located in synapse IDA
IDA: 通过直接分析推断
15911881 MGI
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
15911881 MGI
is active in synaptic vesicle membrane IEP
IEP: 通过表达模式推断
15911881 MGI
is active in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
15911881 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

complexin-3

CPX III

complexin III

lectin, mannose-binding, 1 like

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cplx3 NCBI NCBI:594855