1. Gene
  2. Lrfn5 - leucine rich repeat and fibronectin type III domain containing 5 Gene

Lrfn5 - leucine rich repeat and fibronectin type III domain containing 5 Gene

种属: Mus musculus

同用名: Salm5; mKIAA4208; C130061B21

基因 ID: 238205 | 基因类型: protein coding

关于 Lrfn5

功能概要

Involved in negative regulation of macrophage activation and regulation of presynapse assembly. Located in cell surface. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system; dorsal root ganglion; and retina. Orthologous to human LRFN5 (leucine rich repeat and fibronectin type III domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Lrfn5 基因产物(2)

mRNA Protein Name
NM_001310586.1 NP_001297515.1 leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_178714.5 NP_848829.2 leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27152329 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of macrophage activation IMP
IMP: 通过突变表型推断
27152329 MGI
involved in regulation of presynapse assembly IDA
IDA: 通过直接分析推断
20410109 MGI
involved in regulation of presynapse assembly IMP
IMP: 通过突变表型推断
20410109 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
20410109 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
20410109 MGI
located in cell surface IDA
IDA: 通过直接分析推断
16828986 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20410109 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20410109 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat and fibronectin type-III domain-containing protein 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrfn5 NCBI NCBI:145581