2. Gene
  3. Kdm4d - lysine (K)-specific demethylase 4D Gene

Kdm4d - lysine (K)-specific demethylase 4D Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jmjd2d; 4932416A15

基因 ID: 244694 | 基因类型: protein coding

关于 Kdm4d

功能概要

Enables chromatin DNA binding activity; damaged DNA binding activity; and histone H3-methyl-lysine-9 demethylase activity. Acts upstream of or within cellular response to DNA damage stimulus; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Located in nucleus; pericentric heterochromatin; and site of double-strand break. Orthologous to several human genes including KDM4D (lysine demethylase 4D). [provided by Alliance of Genome Resources, Apr 2022]

Kdm4d 基因产物(2)

mRNA Protein Name
NM_001410506.1 NP_001397435.1 lysine-specific demethylase 4D
NM_173433.3 NP_775609.2 lysine-specific demethylase 4D
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin DNA binding IDA
IDA: 通过直接分析推断
6953429 MGI
enables damaged DNA binding IDA
IDA: 通过直接分析推断
24550317 MGI
enables histone H3K9 demethylase activity IDA
IDA: 通过直接分析推断
16738407 MGI
enables histone H3K9 demethylase activity IMP
IMP: 通过突变表型推断
21293030 MGI
enables histone demethylase activity IDA
IDA: 通过直接分析推断
19144645 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IDA
IDA: 通过直接分析推断
24550317 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
24550317 MGI
located in pericentric heterochromatin IDA
IDA: 通过直接分析推断
16738407 MGI
located in site of double-strand break IDA
IDA: 通过直接分析推断
24550317 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 4D

[histone H3]-trimethyl-L-lysine(9) demethylase 4D

jmjC domain-containing histone demethylation protein 3D

jumonji domain containing 2D

jumonji domain-containing protein 2D

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-104048 QC6352 Inhibitor 99.13% 否
HY-148807 Zavondemstat Inhibitor 99.29% 否
HY-101928 KDM4D-IN-1 Inhibitor 98.82% 否
HY-148807A Zavondemstat L-lysine Inhibitor / 否
HY-RS07216 KDM4D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-148807B (S)-Zavondemstat Control 97.51% 否
HY-173135 PROTAC KDM4 degrader-1 / 否
HY-157408 KDM4D-IN-3 / 否
HY-RS20046 Kdm4d Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26549 Kdm4d Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm4d NCBI NCBI:55693
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