1. Gene
  2. Syn1 - synapsin I Gene

Syn1 - synapsin I Gene

种属: Rattus norvegicus

基因 ID: 24949 | 基因类型: protein coding

关于 Syn1

功能概要

Enables calcium-dependent protein binding activity. Involved in neuron development and synapse organization. Located in several cellular components, including dendrite; presynaptic active zone; and synaptic vesicle. Is anchored component of synaptic vesicle membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in X-linked epilepsy with variable learning disabilities and behavior disorders and non-syndromic X-linked intellectual disability 50. Orthologous to human SYN1 (synapsin I). [provided by Alliance of Genome Resources, Apr 2022]

Syn1 基因产物(2)

mRNA Protein Name
NM_001110782.2 NP_001104252.1 synapsin-1 isoform b
NM_019133.2 NP_062006.1 synapsin-1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
10567243 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11867766 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neuron development IEP
IEP: 通过表达模式推断
27228907 RGD
involved in synapse organization IMP
IMP: 通过突变表型推断
22045728 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
1419001 RGD
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: 通过实验结果推断
23622064 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: 通过直接分析推断
6404912 RGD
located in presynaptic active zone IDA
IDA: 通过直接分析推断
21119615 RGD
located in synapse IDA
IDA: 通过直接分析推断
24613359 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
11867766 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

synapsin-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syn1 NCBI NCBI:6853