2. Gene
  3. Bmp2 - bone morphogenetic protein 2 Gene

Bmp2 - bone morphogenetic protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29373 | 基因类型: protein coding

关于 Bmp2

功能概要

Enables growth factor activity; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including BMP signaling pathway; cellular response to mechanical stimulus; and response to retinoic acid. Acts upstream of or within positive regulation of neurogenesis and positive regulation of transcription by RNA polymerase II. Located in cytoplasm; extracellular space; and vesicle. Part of protein-containing complex. Human ortholog(s) of this gene implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Orthologous to human BMP2 (Bone Morphogenetic Protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Bmp2 基因产物(1)

mRNA Protein Name
NM_017178.2 NP_058874.2 bone morphogenetic protein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor activity IDA
IDA: 通过直接分析推断
12398941 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12871556 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
12871556 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IDA
IDA: 通过直接分析推断
12398941 RGD
involved in cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
26873969 RGD
involved in cellular response to BMP stimulus IEP
IEP: 通过表达模式推断
9246083 RGD
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
20877159 RGD
involved in ovulation cycle IEP
IEP: 通过表达模式推断
15283681 RGD
acts upstream of or within positive regulation of neurogenesis IDA
IDA: 通过直接分析推断
8616889 RGD
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8616889 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
10404008 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
8385738 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18758911 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
12871556 RGD
located in vesicle IDA
IDA: 通过直接分析推断
18758911 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bone morphogenetic protein 2

BMP-2

BMP-2A

bone morphogenetic protein 2A

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-100009 Ufenamate Inhibitor 99.89% 否
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16712 LDN-214117 Inhibitor 99.54% 否
HY-136848 SM1-71 Inhibitor 96.09% 否
HY-N0316 Mollugin 99.48% 否
HY-P0254 Kisspeptin-10, human 99.68% 否
HY-N0265 Asperosaponin VI Inhibitor 98.26% 否
HY-N2375 L-Quebrachitol Activator 98.0% 否
HY-123940 SGC-AAK1-1 Inhibitor 98.93% 否
HY-107245 Segetalin B 99.51% 否
HY-120179 LP-922761 99.73% 否
HY-P0254A Kisspeptin-10, human TFA 99.85% 否
HY-101290A BMT-090605 hydrochloride Inhibitor 98.76% 否
HY-N8920 Syringetin 99.42% 否
HY-142042 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles Inhibitor 99.84% 否
HY-Y1123 2-Aminoacetamide hydrochloride Activator 99.89% 否
HY-135871 BMT-124110 98.93% 否
HY-158203 BMP agonist 2 Agonist 99.26% 否
HY-N0946 (-)-Pinoresinol 4-O-glucoside Inhibitor 98.0% 否
HY-120179A LP-922761 hydrate 98.0% 否
HY-135871A BMT-124110 formic Inhibitor / 否
HY-162653 SGC-CDKL2/AAK1/BMP2K-1 / 否
HY-RS17130 Bmp2k Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-101290 BMT-090605 Inhibitor 98.27% 否
HY-121025 BUR1 Inhibitor 99.65% 否
HY-N16118 Asperosaponin V Modulator / 否
HY-N2682B Dehydrodiconiferyl alcohol Agonist / 否
HY-N8261 Amicoumacin B / 否
HY-RS01536 BMP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01537 BMP2K Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01553 Bmpr2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16626 Bmp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23061 Bmp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23575 Bmp2k Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmp2 NCBI NCBI:650
Mus musculus Bmp2 NCBI NCBI:12156
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