2. Gene
  3. Atp2b1 - ATPase plasma membrane Ca2+ transporting 1 Gene

Atp2b1 - ATPase plasma membrane Ca2+ transporting 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pmca1a; Pmca1b; Pmca1c

基因 ID: 29598 | 基因类型: protein coding

关于 Atp2b1

功能概要

Enables PDZ domain binding activity. Involved in several processes, including calcium ion export; cellular response to lipid; and response to cold. Located in several cellular components, including basolateral plasma membrane; dendritic spine membrane; and neuronal cell body membrane. Is active in GABA-ergic synapse and glutamatergic synapse. Is integral component of presynaptic active zone membrane. Biomarker of hypertension. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1). [provided by Alliance of Genome Resources, Apr 2022]

Atp2b1 基因产物(3)

mRNA Protein Name
NM_001399339.1 NP_001386268.1 plasma membrane calcium-transporting ATPase 1 isoform 2
NM_001399343.1 NP_001386272.1 plasma membrane calcium-transporting ATPase 1 isoform 1
NM_053311.3 NP_445763.1 plasma membrane calcium-transporting ATPase 1 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
16554037 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion export IMP
IMP: 通过突变表型推断
9227424 RGD
involved in cellular response to corticosterone stimulus IEP
IEP: 通过表达模式推断
10777776 RGD
involved in cellular response to vitamin D IEP
IEP: 通过表达模式推断
11277270 RGD
involved in neural retina development IEP
IEP: 通过表达模式推断
16079002 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
23622064 RGD
located in apical part of cell IDA
IDA: 通过直接分析推断
18395836 RGD
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18395836 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16803870 RGD
located in cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
20575074 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
20575074 RGD
located in dendritic spine membrane IDA
IDA: 通过直接分析推断
20575074 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23622064 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
20575074 RGD
is active in presynaptic active zone membrane EXP
EXP: 通过实验结果推断
23622064 RGD
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
23622064 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

plasma membrane calcium-transporting ATPase 1

ATPase, Ca++ transporting, plasma membrane 1

PMCA1

plasma membrane calcium ATPase

plasma membrane calcium pump

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01194 ATP2B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20524 Atp2b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27033 Atp2b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp2b1 NCBI NCBI:490
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