2. Gene
  3. Hmgcs1 - 3-hydroxy-3-methylglutaryl-CoA synthase 1 Gene

Hmgcs1 - 3-hydroxy-3-methylglutaryl-CoA synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29637 | 基因类型: protein coding

关于 Hmgcs1

功能概要

Enables hydroxymethylglutaryl-CoA synthase activity; isomerase activity; and organic acid binding activity. Involved in several processes, including animal organ development; cellular response to cholesterol; and cellular response to follicle-stimulating hormone stimulus. Located in cytosol. Biomarker of obesity. Orthologous to human HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hmgcs1 基因产物(1)

mRNA Protein Name
NM_017268.2 NP_058964.1 hydroxymethylglutaryl-CoA synthase, cytoplasmic
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hydroxymethylglutaryl-CoA synthase activity IDA
IDA: 通过直接分析推断
8094614 RGD
enables isomerase activity IDA
IDA: 通过直接分析推断
17764185 RGD
enables organic acid binding IDA
IDA: 通过直接分析推断
8094614 RGD
enables small molecule binding IDA
IDA: 通过直接分析推断
14984735 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cholesterol IEP
IEP: 通过表达模式推断
18303831 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: 通过表达模式推断
19196834 RGD
involved in cellular response to low-density lipoprotein particle stimulus IDA
IDA: 通过直接分析推断
16260 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
9409294 RGD
involved in liver development IEP
IEP: 通过表达模式推断
5166591 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
11792726 RGD
involved in response to cholesterol IEP
IEP: 通过表达模式推断
2903839 RGD
involved in response to gonadotropin IEP
IEP: 通过表达模式推断
15459111 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
8093833 RGD
involved in response to low light intensity stimulus IEP
IEP: 通过表达模式推断
1683769 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19527300 RGD
involved in response to purine-containing compound IDA
IDA: 通过直接分析推断
16260 RGD
involved in response to tellurium ion IEP
IEP: 通过表达模式推断
10642751 RGD
involved in response to vitamin E IEP
IEP: 通过表达模式推断
15753162 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16020911 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hydroxymethylglutaryl-CoA synthase, cytoplasmic

3-hydroxy-3-methylglutaryl coenzyme A synthase

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)

HMG-CoA synthase

hydroxymethylglutaryl-CoA synthase 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06241 HMGCS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18093 Hmgcs1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24568 Hmgcs1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24905 Hmgcs2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hmgcs1 NCBI NCBI:3157
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