2. Gene
  3. Hsp90ab1 - heat shock protein 90 alpha family class B member 1 Gene

Hsp90ab1 - heat shock protein 90 alpha family class B member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: HSPC2; Hspcb; HSP90B; HSP90-BETA

基因 ID: 301252 | 基因类型: protein coding

关于 Hsp90ab1

功能概要

Enables nucleotide binding activity; sulfonylurea receptor binding activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of complement-dependent cytotoxicity; positive regulation of protein import into nucleus; and regulation of cellular protein metabolic process. Located in several cellular components, including basolateral plasma membrane; brush border membrane; and ooplasm. Biomarker of muscular atrophy; pancreatitis; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human HSP90AB1 (heat shock protein 90 alpha family class B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsp90ab1 基因产物(1)

mRNA Protein Name
NM_001004082.3 NP_001004082.3 heat shock protein HSP 90-beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
12755697 RGD
enables CTP binding IDA
IDA: 通过直接分析推断
12755697 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
12755697 RGD
enables UTP binding IDA
IDA: 通过直接分析推断
12755697 RGD
enables dATP binding IDA
IDA: 通过直接分析推断
12755697 RGD
enables heterocyclic compound binding IPI
IPI: 通过物理相互作用推断
18218611 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
18644871 RGD
enables protein folding chaperone IMP
IMP: 通过突变表型推断
17517623 RGD
enables sulfonylurea receptor binding IPI
IPI: 通过物理相互作用推断
20427569 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
20427569 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
10617604 RGD
involved in chaperone-mediated protein folding IMP
IMP: 通过突变表型推断
17517623 RGD
involved in negative regulation of complement-dependent cytotoxicity IMP
IMP: 通过突变表型推断
16135098 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
18443201 RGD
involved in negative regulation of proteasomal protein catabolic process IMP
IMP: 通过突变表型推断
17517623 RGD
involved in positive regulation of cell size IMP
IMP: 通过突变表型推断
20980790 RGD
involved in positive regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
20980790 RGD
involved in positive regulation of protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
18443201 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
22860061 RGD
involved in response to salt stress IEP
IEP: 通过表达模式推断
15497505 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
24478030 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
15497505 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15497505 RGD
located in brush border membrane IDA
IDA: 通过直接分析推断
15497505 RGD
located in cell surface IDA
IDA: 通过直接分析推断
19948165 RGD
located in inclusion body IDA
IDA: 通过直接分析推断
18445155 RGD
located in lysosomal membrane IDA
IDA: 通过直接分析推断
18644871 RGD
located in ooplasm IDA
IDA: 通过直接分析推断
19022436 RGD
part of protein folding chaperone complex IMP
IMP: 通过突变表型推断
17517623 RGD
located in sperm head plasma membrane IDA
IDA: 通过直接分析推断
24478030 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock protein HSP 90-beta

HSP 84

HSP84

heat shock 84 kDa

heat shock 90kDa protein 1, beta

heat shock protein 90 alpha (cytosolic), class B member 1

heat shock protein 90kDa alpha (cytosolic), class B member 1

heat shock protein 90kDa alpha family class B member 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123035 Gamendazole Inhibitor 99.44% 否
HY-RS06418 HSP90AB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18017 Hsp90ab1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24490 Hsp90ab1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hsp90ab1 NCBI NCBI:3326
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