1. Gene
  2. MFF - Mff mitochondrial fission factor Gene

MFF - Mff mitochondrial fission factor Gene

种属: Rattus norvegicus

同用名: RGD1310230

基因 ID: 301563 | 基因类型: protein coding

关于 MFF

功能概要

Enables GTPase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of cellular component organization. Located in synaptic vesicle. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Used to study transient cerebral ischemia. Orthologous to human MFF (mitochondrial fission factor). [provided by Alliance of Genome Resources, Apr 2022]

MFF 基因产物(3)

mRNA Protein Name
NM_001039015.2 NP_001034104.1 mitochondrial fission factor isoform 2
NM_001271284.1 NP_001258213.1 mitochondrial fission factor isoform 1
NM_001276401.1 NP_001263330.1 mitochondrial fission factor isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase binding IPI
IPI: 通过物理相互作用推断
23792689 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
23792689 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
23792689 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
23867156 RGD
involved in positive regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
23867156 RGD
involved in positive regulation of mitochondrial fission IMP
IMP: 通过突变表型推断
23867156 RGD
involved in positive regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
23792689 RGD
involved in protein targeting to mitochondrion IMP
IMP: 通过突变表型推断
23792689 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial membrane IMP
IMP: 通过突变表型推断
23792689 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
23792689 RGD
located in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
23792689 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mitochondrial fission factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MFF NCBI NCBI:56947