Dysf - dysferlin Gene

种属: Rattus norvegicus

关于 Dysf

功能概要

Predicted to enable calcium ion binding activity; calcium-dependent phospholipid binding activity; and tubulin binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; negative regulation of phagocytosis; and plasma membrane organization. Predicted to act upstream of or within several processes, including negative regulation of macromolecule metabolic process; positive regulation of neutrophil chemotaxis; and regulation of calcium ion transport. Located in cytoplasm. Human ortholog(s) of this gene implicated in Miyoshi muscular dystrophy 1; autosomal recessive limb-girdle muscular dystrophy type 2B; distal muscular dystrophy with anterior tibial onset; and muscular dystrophy. Orthologous to human DYSF (dysferlin). [provided by Alliance of Genome Resources, Apr 2022]