2. Gene
  3. Manf - mesencephalic astrocyte-derived neurotrophic factor Gene

Manf - mesencephalic astrocyte-derived neurotrophic factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Armet

基因 ID: 315989 | 基因类型: protein coding

关于 Manf

功能概要

Predicted to enable sulfatide binding activity. Predicted to be involved in dopaminergic neuron differentiation; neuron projection development; and regulation of response to endoplasmic reticulum stress. Predicted to act upstream of or within vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure. Located in extracellular space and perinuclear region of cytoplasm. Colocalizes with endoplasmic reticulum. Human ortholog(s) of this gene implicated in Parkinsonism; breast cancer; carcinoma (multiple); and pancreatic Cancer. Orthologous to human MANF (mesencephalic astrocyte derived neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]

Manf 基因产物(1)

mRNA Protein Name
NM_001401064.1 NP_001387993.1 mesencephalic astrocyte-derived neurotrophic factor precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19641128 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19641128 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mesencephalic astrocyte-derived neurotrophic factor

arginine-rich protein

arginine-rich, mutated in early stage tumors

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08017 MANF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18040 Manf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24514 Manf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Manf NCBI NCBI:7873
Mus musculus Manf NCBI NCBI:74840
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