2. Gene
  3. Top2b - DNA topoisomerase II beta Gene

Top2b - DNA topoisomerase II beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 361100 | 基因类型: protein coding

关于 Top2b

功能概要

Enables ribonucleoprotein complex binding activity. Involved in several processes, including cellular response to ATP; cellular response to hydrogen peroxide; and positive regulation of double-strand break repair via nonhomologous end joining. Located in nucleolus. Orthologous to human TOP2B (DNA Topoisomerase II beta). [provided by Alliance of Genome Resources, Apr 2022]

Top2b 基因产物(1)

mRNA Protein Name
NM_001100858.2 NP_001094328.2 DNA topoisomerase 2-beta
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ribonucleoprotein complex binding IPI
IPI: 通过物理相互作用推断
20554522 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to ATP IDA
IDA: 通过直接分析推断
25034690 RGD
involved in cellular response to hydrogen peroxide IDA
IDA: 通过直接分析推断
22019940 RGD
involved in cellular senescence IEP
IEP: 通过表达模式推断
20708677 RGD
involved in positive regulation of double-strand break repair via nonhomologous end joining IMP
IMP: 通过突变表型推断
22019940 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA topoisomerase 2-beta

topoisomerase (DNA) II beta

topoisomerase II beta

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-174374 Topobexin Inhibitor 99.04% 否
HY-RS14897 TOP2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-123393 PNU-142586 Inhibitor / 否
HY-175834 DNA/TOP2A-IN-1 / 否
HY-RS20119 Top2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26623 Top2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Top2b NCBI NCBI:7155
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