2. Gene
  3. Tp73 - tumor protein p73 Gene

Tp73 - tumor protein p73 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: P73; Trp73

基因 ID: 362675 | 基因类型: protein coding

关于 Tp73

功能概要

Enables sequence-specific DNA binding activity. Involved in several processes, including negative regulation of neuron differentiation; positive regulation of MAPK cascade; and positive regulation of oligodendrocyte differentiation. Located in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; primary ciliary dyskinesia; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73). [provided by Alliance of Genome Resources, Apr 2022]

Tp73 基因产物(1)

mRNA Protein Name
NM_001108696.1 NP_001102166.1 tumor protein p73
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15805112 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in kidney development IEP
IEP: 通过表达模式推断
15805112 RGD
involved in negative regulation of neuron differentiation IMP
IMP: 通过突变表型推断
17353261 RGD
involved in positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
17353261 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
15716325 RGD
involved in positive regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
14960496 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
20519366 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
15805112 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor protein p73

transformation related protein 73

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14924 TP73 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26467 Tp73 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tp73 NCBI NCBI:7161
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