MIR382 - microRNA 382 Gene

中文名称：微小 RNA 382

种属: Homo sapiens

同用名: MIRN382; mir-382; hsa-mir-382

基因 ID: 494331 | 基因类型: ncRNA

关于 MIR382

This gene has 1 transcript (splice variant), 22 orthologues and 16 paralogues.

功能概要

微小 RNA (miRNA) 是短的 (20-24 nt) 非编码 RNA，通过影响 mRNA 的稳定性和翻译，参与多细胞生物中基因表达的转录后调控。 miRNA 由 RNA 聚合酶 II 转录，作为加帽和聚腺苷酸化初级转录物 (pri-miRNA) 的一部分，可以是蛋白质编码或非编码的。初级转录物被 Drosha 核糖核酸酶 III 酶切产生大约 70 nt 的茎环前体 miRNA (pre-miRNA) ，它被细胞质 Dicer 核糖核酸酶进一步切割以产生成熟的 miRNA 和反义 miRNA 星 (miRNA * ) 产品。成熟的 miRNA 被整合到 RNA 诱导的沉默复合体 (RISC) 中，它通过与 miRNA 的不完美碱基配对识别靶 mRNA，最常见的结果是靶 mRNA 的翻译抑制或不稳定。 RefSeq 代表预测的 MicroRNA 茎环。[RefSeq 提供，2009 年 9 月]

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III Enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

关联疾病

疾病名称

别名

Polymyositis

Pm - [Polymyositis]

Muscular Dystrophy, Duchenne Type

Duchenne Muscular Dystrophy	DMD
Muscular Dystrophy, Duchenne	Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type
Severe Dystrophinopathy, Duchenne Type	Muscular Dystrophy Duchenne
Dystrophy, Muscular, Duchenne Type	Benign Duchenne Muscular Dystrophy
Duchenne Motor Neuron Disease	Duchenne Type Dystrophy
Duchenne-Griesinger Disease

Dermatomyositis

Amyopathic Dermatomyositis	Dermatopolymyositis
Adult Dermatomyositis	Polymyositis With Skin Involvement
Adult Type Dermatomyositis	Petges-Clejat Syndrome

Nemaline Myopathy

Rod Myopathy	Nemaline Body Disease
Nemaline Rod Myopathy	Myopathies, Nemaline
Nm	Nemaline Rod Disease
Rod Body Disease	Rod-Body Myopathy
Myopathy, Nemaline	Congenital Rod Disease
Nem	Nemaline Bodies
Myopathies Nemaline

Bone Resorption Disease

Bone Resorption

Laryngeal Disease

Laryngeal Diseases

Bone Remodeling Disease

Muscular Dystrophy, Congenital, Megaconial Type

Megaconial Type Congenital Muscular Dystrophy	Congenital Megaconial Myopathy
Congenital Muscular Dystrophy Due To Phosphatidylcholine Biosynthesis Defect	Congenital Muscular Dystrophy With Mitochondrial Structural Abnormalities
Megaconial Congenital Muscular Dystrophy	MDCMC
Muscular Dystrophy, Congenital, With Mitochondrial Structural Abnormalities	Megaconial Congénital Muscular Dystrophy
Dystrophy, Muscular, Congenital, Megaconial Type

Endocrine System Disease

Abnormality Of The Endocrine System	Disorder Of Endocrine System
Endocrine System Diseases

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Aortic Valve Disease 2

Aortic Valve Stenosis	Aortic Stenosis
Rheumatic Aortic Stenosis	AOVD2
Bicuspid Aortic Valve	Rheumatic Aortic Valve Stenosis
Valvular Aortic Stenosis	Aortic Valve Disease, Type 2
Aortic Valve Stricture	Aortic Valve Obstruction
Obstructed Aorta Valve	Rheumatic Aortic Obstruction
Rheumatic Aortic Valve Obstruction	Rheumatic Aortic Stricture
Aortic Valve Regurgitation	Aortic Insufficiency With Stenosis
Rheumatic Aortic Valve Stenosis With Insufficiency	Rheumatic Aortic Stenosis With Incompetence
Rheumatic Aortic Stenosis With Regurgitation

Connective Tissue Disease

Connective Tissue Diseases	Connective Tissue Disorder
Abnormality Of Connective Tissue	Disorder Of Connective Tissue
Connective Tissue Disorders

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma	Lymphoma, Non-Hodgkin
NHL	Lymphoma, Non-Hodgkin, Somatic
Lymphoma, Follicular, Somatic	Familial Non-Hodgkin Lymphoma
Lymphoma Non-Hodgkins	Follicular Lymphoma, Somatic
Lymphosarcoma	Non-Hodgkins Lymphoma

Nervous System Disease

Abnormality Of The Nervous System	Nervous System Diseases
Nervous System Disorder

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Type 2 Diabetes	Diabetes Mellitus, Non-Insulin-Dependent
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	纯度	是否罕见病
HY-R00861	hsa-miR-382-5p mimic	93.14%	否
HY-RI00861	hsa-miR-382-5p inhibitor	96.05%	否
HY-R00860	hsa-miR-382-3p mimic	/	否
HY-R00860A	hsa-miR-382-3p agomir	/	否
HY-R00861A	hsa-miR-382-5p agomir	/	否
HY-R03120	mmu-miR-382-3p mimic	/	否
HY-R03120A	mmu-miR-382-3p agomir	/	否
HY-RI00860	hsa-miR-382-3p inhibitor	/	否
HY-RI00860A	hsa-miR-382-3p antagomir	/	否
HY-RI00861A	hsa-miR-382-5p antagomir	/	否
HY-RI03120	mmu-miR-382-3p inhibitor	/	否
HY-RI03120A	mmu-miR-382-3p antagomir	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	MIR382	MGD	MGI:3619392

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

MIR382 - microRNA 382 Gene

关于 MIR382

功能概要

关联疾病

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MIR382 - microRNA 382 Gene

关于 MIR382

功能概要

关联疾病

相关产品

直系同源

热门区域

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B

C

F

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Q

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