2. Gene
  3. Sox2 - SRY-box transcription factor 2 Gene

Sox2 - SRY-box transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1565646

基因 ID: 499593 | 基因类型: protein coding

关于 Sox2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including adenohypophysis development; positive regulation of transcription by RNA polymerase II; and tissue regeneration. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer; nasal cavity cancer; and syndromic microphthalmia 3. Orthologous to human SOX2 (SRY-box transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sox2 基因产物(1)

mRNA Protein Name
NM_001109181.2 NP_001102651.1 transcription factor SOX-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12637543 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12637543 RGD
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
12637543 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenohypophysis development IEP
IEP: 通过表达模式推断
21815952 RGD
involved in positive regulation of cell differentiation IMP
IMP: 通过突变表型推断
19161985 RGD
involved in positive regulation of cell-cell adhesion IMP
IMP: 通过突变表型推断
20869108 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12637543 RGD
involved in regulation of myofibroblast cell apoptotic process IMP
IMP: 通过突变表型推断
34321385 RGD
involved in response to oxygen-glucose deprivation IMP
IMP: 通过突变表型推断
34321385 RGD
involved in tissue regeneration IEP
IEP: 通过表达模式推断
19845688 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12637543 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-2

SRY (sex determining region Y)-box 2

SRY box 2

SRY-box containing gene 2

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12303 OAC1 Activator 99.56% 否
HY-B1238 Pronethalol Inhibitor 99.73% 否
HY-18772 O4I2 Activator 99.30% 否
HY-150082 CP681301 Inhibitor 99.18% 否
HY-RS13591 SOX2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-143443 DS17701585 Inhibitor / 否
HY-B1238A Pronethalol hydrochloride Inhibitor / 否
HY-119666 Rooperol Activator / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox2 NCBI NCBI:6657
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