Dnai1 - dynein, axonemal, intermediate chain 1 Gene

种属: Rattus norvegicus

同用名: Dnaic1

关于 Dnai1

功能概要

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in flagellated sperm motility; Insulin Receptor signaling pathway; and outer dynein arm assembly. Predicted to act upstream of or within determination of left/right symmetry; epithelial cilium movement involved in extracellular fluid movement; and heart development. Predicted to be located in 9+2 motile cilium; centrosome; and cytoplasm. Predicted to be part of outer dynein arm. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]