2. Gene
  3. Ldlrap1 - low density lipoprotein receptor adaptor protein 1 Gene

Ldlrap1 - low density lipoprotein receptor adaptor protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1563417

基因 ID: 500564 | 基因类型: protein coding

关于 Ldlrap1

功能概要

Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and amyloid-beta binding activity. Predicted to be involved in several processes, including low-density lipoprotein particle clearance; positive regulation of low-density lipoprotein particle clearance; and receptor-mediated endocytosis. Predicted to act upstream of or within Cholesterol homeostasis. Located in axon. Human ortholog(s) of this gene implicated in autosomal recessive hypercholesterolemia. Orthologous to human LDLRAP1 (low density lipoprotein receptor adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ldlrap1 基因产物(1)

mRNA Protein Name
NM_001109271.1 NP_001102741.1 low density lipoprotein receptor adapter protein 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14528014 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
17727637 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low density lipoprotein receptor adapter protein 1

autosomal recessive hypercholesterolemia protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07580 LDLRAP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ldlrap1 NCBI NCBI:26119
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