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  2. P2RY4 - pyrimidinergic receptor P2Y4 Gene

P2RY4 - pyrimidinergic receptor P2Y4 Gene

中文名称:嘧啶能受体 P2Y4

种属: Homo sapiens

同用名: NRU; P2P; UNR; P2Y4

基因 ID: 5030 | 基因类型: protein coding

关于 P2RY4

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,258,166-70,260,204 (from NCBI)

This gene has 1 transcript (splice variant), 168 orthologues and 15 paralogues.

功能概要

该基因的产物属于G蛋白偶联受体家族。该家族有几种受体亚型,具有不同的药理选择性,在某些情况下,它们对各种腺苷和尿苷核苷酸有重叠。该受体对尿苷核苷酸有反应,对 ATP 有部分反应,对 ADP 无反应。[由 RefSeq 提供,2008 年 7 月]

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008]

P2RY4 基因产物(1)

mRNA Protein Name
NM_002565.4 NP_002556.1 P2Y purinoceptor 4
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

P2RY4 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (53 - 306)

  • 0
  • 100
  • 200
  • 300
  • 365 a.a.
蛋白主名 其他名称

P2Y purinoceptor 4

pyrimidinergic receptor P2Y, G-protein coupled, 4

uridine nucleotide receptor

P2RY4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
P2RY4 P51582 OPTN Homo sapiens Q96CV9 32814053
种属内
P2RY4 P51582 OPTN Homo sapiens Q96CV9 32814053
种属内
P2RY4 P51582 OPTN Homo sapiens Q96CV9 32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

P2RY4 抗体

目录号 产品名 应用 反应物种
HY-P84370 P2RY4 Antibody (YA4067) WB, IHC-P, ELISA Human
HY-P84371 P2RY4 Antibody (YA4068) IHC-P, ICC/IF, FC, ELISA Human

关联疾病

疾病名称 别名
Desmoid Disease, Hereditary

Fif

DESMD

Hereditary Desmoid Disease

Familial Infiltrative Fibromatosis

Fibromatosis, Familial Infiltrative

Fibromatosis, Aggressive

Infiltrative Basal Cell Carcinoma

Skin Infiltrating Basal Cell Carcinoma

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta P2RY4 VGNC VGNC:75739
Bos taurus P2RY4 VGNC VGNC:32529
Rattus norvegicus P2RY4 RGD RGD:61798
Mus musculus P2RY4 MGD MGI:1926594
Felis catus P2RY4 VGNC VGNC:68675