2. Gene
  3. Prf1 - perforin 1 Gene

Prf1 - perforin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cyta; RATCYTA

基因 ID: 50669 | 基因类型: protein coding

关于 Prf1

功能概要

Predicted to enable calcium ion binding activity; identical protein binding activity; and wide pore channel activity. Involved in apoptotic process; circadian rhythm; and response to ethanol. Located in cytoplasmic vesicle and extracellular space. Used to study asthma; colon carcinoma; and glomerulonephritis. Biomarker of membranoproliferative glomerulonephritis. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Orthologous to human PRF1 (perforin 1). [provided by Alliance of Genome Resources, Apr 2022]

Prf1 基因产物(1)

mRNA Protein Name
NM_017330.2 NP_059026.2 perforin-1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IMP
IMP: 通过突变表型推断
16309885 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
14978081 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17622272 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

perforin-1

P1

cytolysin

lymphocyte pore-forming protein

perforin 1 (pore forming protein)

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11087 PRF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16136 ZNF395 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19938 Prf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26440 Prf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prf1 NCBI NCBI:5551
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