1. Gene
  2. Eml1 - echinoderm microtubule associated protein like 1 Gene

Eml1 - echinoderm microtubule associated protein like 1 Gene

种属: Mus musculus

同用名: EMAP; heco; ELP79; EMAPL; EMAP-1; 1110008N23Rik; A930030P13Rik

基因 ID: 68519 | 基因类型: protein coding

关于 Eml1

功能概要

Enables microtubule binding activity. Involved in brain development; mitotic spindle organization; and neuroblast proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in cytosol. Colocalizes with mitotic spindle midzone and mitotic spindle pole. Is expressed in Sertoli cell; liver; lung; nervous system; and retina. Used to study congenital nervous system abnormality and subcortical band heterotopia. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Orthologous to human EML1 (EMAP like 1). [provided by Alliance of Genome Resources, Apr 2022]

Eml1 基因产物(11)

mRNA Protein Name
NM_001043335.1 NP_001036800.1 echinoderm microtubule-associated protein-like 1 isoform 1
NM_001043336.2 NP_001036801.1 echinoderm microtubule-associated protein-like 1 isoform 2
NM_001286346.1 NP_001273275.1 echinoderm microtubule-associated protein-like 1 isoform 3
NM_001286347.1 NP_001273276.1 echinoderm microtubule-associated protein-like 1 isoform 4
NM_001364193.1 NP_001351122.1 echinoderm microtubule-associated protein-like 1 isoform 5
NM_001364194.1 NP_001351123.1 echinoderm microtubule-associated protein-like 1 isoform 6
NM_001364195.1 NP_001351124.1 echinoderm microtubule-associated protein-like 1 isoform 7
NM_001364196.1 NP_001351125.1 echinoderm microtubule-associated protein-like 1 isoform 4
NM_001364197.1 NP_001351126.1 echinoderm microtubule-associated protein-like 1 isoform 2
NM_001364198.1 NP_001351127.1 echinoderm microtubule-associated protein-like 1 isoform 8
NM_001364199.1 NP_001351128.1 echinoderm microtubule-associated protein-like 1 isoform 9
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microtubule binding IDA
IDA: 通过直接分析推断
24859200 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in brain development IMP
IMP: 通过突变表型推断
24859200 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
24029230 MGI
involved in microtubule cytoskeleton organization IMP
IMP: 通过突变表型推断
24859200 MGI
involved in mitotic spindle organization IMP
IMP: 通过突变表型推断
24859200 MGI
involved in neuroblast proliferation IMP
IMP: 通过突变表型推断
24859200 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
24859200 MGI
colocalizes with mitotic spindle midzone IMP
IMP: 通过突变表型推断
24859200 MGI
colocalizes with mitotic spindle pole IMP
IMP: 通过突变表型推断
24859200 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

echinoderm microtubule-associated protein-like 1

echinoderm microtubule associated protein-like protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eml1 NCBI NCBI:2009