SYT5 - synaptotagmin 5 Gene

中文名称：突触结合蛋白 5

种属: Homo sapiens

关于 SYT5

功能概要

突触结合蛋白，例如 SYT5，是一个 III 型膜蛋白家族，其特征在于与蛋白激酶 C (参见 MIM 176960) 调节 (C2) 结构域相关的细胞质重复序列，其被认为可结合钙。突触结合蛋白既可以作为囊泡融合的负调节因子，允许在钙存在下融合，也可以作为钙受体或传感器分子 (Hudson 和 Birnbaum 总结，1995 [PubMed 7597049]) 。[OMIM 提供，2011 年 2 月]

Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]