ZNF711 - zinc finger protein 711 Gene

中文名称：锌指蛋白 711

种属: Homo sapiens

同用名: ZNF4; ZNF5; ZNF6; CMPX1; MRX65; MRX97; XLID97; Zfp711; dJ75N13.1

基因 ID: 7552 | 基因类型: protein coding

关于 ZNF711

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:85,243,991-85,273,357 (from NCBI)

This gene has 4 transcripts (splice variants), 218 orthologues, 38 paralogues and is associated with 3 phenotypes. Broad expression in testis (RPKM 23.7), brain (RPKM 10.7) and 16 other tissues.

功能概要

该基因编码一种功能未知的锌指蛋白。它与充当转录激活剂的锌指蛋白具有相似性。该基因位于 X 染色体的一个区域，该区域与认知障碍有关。[RefSeq 提供，2008 年 7 月]

This gene encodes a Zinc Finger Protein of unknown function. It bears similarity to a Zinc Finger Protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with cognitive disability. [provided by RefSeq, Jul 2008]

ZNF711 基因产物(9)

mRNA	Protein	Name
NM_001330574.2	NP_001317503.1	zinc finger protein 711 isoform 1
NM_001375431.1	NP_001362360.1	zinc finger protein 711 isoform 1
NM_001375432.1	NP_001362361.1	zinc finger protein 711 isoform 1
NM_001375433.1	NP_001362362.1	zinc finger protein 711 isoform 1
NM_001375434.1	NP_001362363.1	zinc finger protein 711 isoform 2
NM_001375435.1	NP_001362364.1	zinc finger protein 711 isoform 2
NM_001375436.1	NP_001362365.1	zinc finger protein 711 isoform 2
NM_001375437.1	NP_001362366.1	zinc finger protein 711 isoform 2
NM_021998.5	NP_068838.3	zinc finger protein 711 isoform 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	20346720	GOA
enables sequence-specific DNA binding	IDA IDA: 通过直接分析推断	20346720	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of DNA-templated transcription	IMP IMP: 通过突变表型推断	20346720	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: 通过直接分析推断	31691806	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in nucleus	IDA IDA: 通过直接分析推断	20346720	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF711 蛋白结构

Zfx_Zfy_act

zf-C2H2

zf-H2C2_5

zf-H2C2_2

zf-C2H2_4

zf-H2C2_2

zf-H2C2_5

zf-H2C2_2

zf-C2H2_4

0
200
400
600
761 a.a.

蛋白主名

其他名称

zinc finger protein 711

dJ75N13.1 (znf6-like)

关联疾病

疾病名称

别名

Intellectual Developmental Disorder, X-Linked 97

XLID97	Mental Retardation, X-Linked 97
Mrx97	Mrx65
Mrxz	Mental Retardation, X-Linked 65
Mental Retardation, X-Linked, Type 97	Mental Retardation, X-Linked, Znf711-Related

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

Non-Syndromic X-Linked Intellectual Disability 97

Mrx65	Mrx97
Mrxz	X-Linked Mental Retardation 65
X-Linked Mental Retardation 97

Partington Syndrome

X-Linked Reticulate Pigmentary Disorder	PRTS
Partington X-Linked Mental Retardation Syndrome	Mrxs1
Mrx36	Intellectual Developmental Disorder, X-Linked, Syndromic 1
Partington Disease	Pdr
Partington-Mulley Syndrome	Russell-Silver Syndrome, X-Linked
Mental Retardation, X-Linked, Syndromic 1	Mental Retardation, X-Linked, With Dystonic Movements, Ataxia, And Seizures
Mental Retardation, X-Linked 36	X-Linked Reticulate Pigmentary Disorder With Systemic Manifestations
X-Linked Russell-Silver Syndrome	Intelectual Disability-Dystonic Movements-Ataxia-Seizures Syndrome
Intellectual Disability, X-Linked, Syndromic 1	Intellectual Disability, X-Linked, With Dystonic Movements, Ataxia, And Seizures
Partington X-Linked Intellectual Disability Syndrome	X-Linked Intellectual Deficit-Dystonia-Dysarthria
X-Linked Mental Retardation With Dystonic Movements, Ataxia, And Seizures	Familial Cutaneous Amyloidosis
X-Linked Cutaneous Amyloidosis	Xlpdr
X-Linked Intellectual Disability-Dystonia-Dysarthria Syndrome	Pigmentary Disorder, Reticulate, With Systemic Manifestations

Syndromic X-Linked Intellectual Disability Siderius Type

Mrxssd	Siderius-Hamel Syndrome
Siderius X-Linked Mental Retardation Syndrome

Familial Behcet-Like Autoinflammatory Syndrome

Autoinflammatory Syndrome, Familial, Behcet-Like

A20 Haploinsufficiency

Corpus Callosum, Agenesis Of, With Abnormal Genitalia

Proud Syndrome	Corpus Callosum Agenesis-Abnormal Genitalia Syndrome
Acc With Abnormal Genitalia	Proud-Levine-Carpenter Syndrome
Microcephaly-Corpus Callosum Agenesis-Abnormal Genitalia Syndrome	Corpus Callosum Agenesis With Abnormal Genitalia
New X-Linked Syndrome With Seizures, Acquired Micrencephaly, And Agenesis Of The Corpus Callosum	Proud Levine Carpenter Syndrome
Acc-Abnormal Genitalia Syndrome	Agenesis Of The Corpus Callosum, With Abnormal Genitalia
ACCAG	Micrencephaly-Corpus Callosum Agenesis-Abnormal Genitalia
Congenital Neurologic Anomalies

Bleeding Disorder, Platelet-Type, 17

Platelet-Type Bleeding Disorder 17	BDPLT17
Thrombasthenia-Thrombocytopenia, Hereditary	Hereditary Thrombasthenia-Thrombocytopenia
Autosomal Dominant Macrothrombocytopenia Gfi1b-Related	Autosomal Dominant Platelet Disorder Gfi1b-Related
Bleeding Disorder, Platelet Type 17

Developmental And Epileptic Encephalopathy 1

Epileptic Encephalopathy, Early Infantile, 1	Infantile Epileptic-Dyskinetic Encephalopathy
DEE1	Eiee1
Issx1	Xmesid
X-Linked Infantile Spasm Syndrome 1	X-Linked Infantile Spasm Syndrome
X-Linked Spasticity-Intellectual Disability-Epilepsy Syndrome	Developmental And Epileptic Encephalopathy, 1
Infantile Epileptic Dyskinetic Encephalopathy	Infantile Spasm Syndrome, X-Linked 1
West Syndrome, X-Linked	Ohtahara Syndrome, X-Linked
Early Infantile Epileptic Encephalopathy 1	Early Infantile Epileptic Encephalopathy-1
Issx	X-Linked Ohtahara Syndrome
X-Linked West Syndrome	Infantile Spasm Syndrome X-Linked 1
Myoclonic Epilepsy X-Linked With Intellectual Disability And Spasticity	Ohtahara Syndrome X-Linked
West Syndrome X-Linked	Encephalopathy, Epileptic, Early Infantile, Type 1

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Syndromic Intellectual Disability

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS16169	ZNF711 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	ZNF711	RGD	RGD:1562768
Mus musculus	ZNF711	MGD	MGI:3045342
Bos taurus	ZNF711	VGNC	VGNC:37337
Canis familiaris	ZNF711	VGNC	VGNC:48806

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