2. Gene
  3. CPEB4 - cytoplasmic polyadenylation element binding protein 4 Gene

CPEB4 - cytoplasmic polyadenylation element binding protein 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞质聚腺苷酸化元件结合蛋白 4

种属: Homo sapiens

同用名: CPE-BP4; hCPEB-4

基因 ID: 80315 | 基因类型: protein coding

关于 CPEB4

Cytogenetic location: 5q35.2 Genomic coordinates (GRCh38): 5:173,888,349-173,961,980 (from NCBI)

This gene has 13 transcripts (splice variants), 285 orthologues and 3 paralogues. Ubiquitous expression in adrenal (RPKM 26.5), bone marrow (RPKM 18.8) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与多个过程，包括细胞对葡萄糖饥饿的反应；细胞质翻译的负调控；和对缺血的反应。位于细胞质和细胞核中。肝硬化生物标志物；门静脉高压症;和原发性胆汁性胆管炎。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of cytoplasmic translation; and response to ischemia. Located in cytoplasm and nucleus. Biomarker of liver cirrhosis; portal hypertension; and primary biliary cholangitis. [provided by Alliance of Genome Resources, Apr 2022]

CPEB4 基因产物(5)

mRNA Protein Name
NM_001308189.2 NP_001295118.1 cytoplasmic polyadenylation element-binding protein 4 isoform b
NM_001308191.2 NP_001295120.1 cytoplasmic polyadenylation element-binding protein 4 isoform c
NM_001308192.2 NP_001295121.1 cytoplasmic polyadenylation element-binding protein 4 isoform d
NM_001308193.2 NP_001295122.1 cytoplasmic polyadenylation element-binding protein 4 isoform e
NM_030627.4 NP_085130.2 cytoplasmic polyadenylation element-binding protein 4 isoform a
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21336257 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
20639532 GOA
located in nucleus IDA
IDA: 通过直接分析推断
20639532 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CPEB4 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (474 - 535)

  • 0
  • 200
  • 400
  • 600
  • 729 a.a.
蛋白主名 其他名称

cytoplasmic polyadenylation element-binding protein 4

CPE-binding protein 4

关联疾病

疾病名称 别名
Portal Hypertension

Hypertension, Portal

Hypertension Portal

Pht - [Portal Hypertension]

Portal Htn
Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Biliary Liver Cirrhosis

Chronic Nonsuppurative Destructive Cholangitis

Familial Primary Biliary Cirrhosis

Pbc

Hanot Syndrome

Cholestatic Cirrhosis

Biliary Cirrhosis Primary

Liver Cirrhosis, Biliary

Hanot'S Cirrhosis

Biliary Cirrhosis

Pericholangiolic Biliary Cirrhosis

Tannhauser-Magendantz Syndrome

Hanot-Rossle Syndrome

Hypertrophic Cirrhosis

Todd Cirrhosis

Hanot Cirrhosis

Charcot Cirrhosis

Mahon-Tannhauser Syndrome

Toxic Cirrhosis

Hypertrophic Biliary Cirrhosis

Monolobular Cirrhosis

Unilobar Cirrhosis

Xanthomatous Biliary Cirrhosis
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10778 me4 Peptide / 否
HY-RS03094 CPEB4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20386 Cpeb4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26896 Cpeb4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CPEB4 VGNC VGNC:39554
Mus musculus CPEB4 MGD MGI:1914829
Bos taurus CPEB4 VGNC VGNC:27650
Felis catus CPEB4 VGNC VGNC:61121
Macaca mulatta CPEB4 VGNC VGNC:71450
Rattus norvegicus CPEB4 RGD RGD:1311931
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z