1. Gene
  2. Ica1 - islet cell autoantigen 1 Gene

Ica1 - islet cell autoantigen 1 Gene

种属: Rattus norvegicus

同用名: Ica69

基因 ID: 81024 | 基因类型: protein coding

关于 Ica1

功能概要

Enables protein domain specific binding activity. Involved in regulation of protein-containing complex assembly. Located in Golgi apparatus; dendrite; and perinuclear region of cytoplasm. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1). [provided by Alliance of Genome Resources, Apr 2022]

Ica1 基因产物(1)

mRNA Protein Name
NM_030844.2 NP_110471.2 islet cell autoantigen 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein domain specific binding IMP
IMP: 通过突变表型推断
18032668 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of protein-containing complex assembly IMP
IMP: 通过突变表型推断
18032668 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi membrane IDA
IDA: 通过直接分析推断
12682071 RGD
located in Golgi stack IDA
IDA: 通过直接分析推断
12682071 RGD
located in dendrite IDA
IDA: 通过直接分析推断
18032668 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
12682071 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

islet cell autoantigen 1

69 kDa islet cell autoantigen

ICAp69

islet cell autoantigen 1, 69 kDa

islet cell autoantigen p69

p69

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ica1 NCBI NCBI:3382
Mus musculus Ica1 NCBI NCBI:15893