2. Gene
  3. Hamp - hepcidin antimicrobial peptide Gene

Hamp - hepcidin antimicrobial peptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Hepc

基因 ID: 84604 | 基因类型: protein coding

关于 Hamp

功能概要

Predicted to enable copper ion binding activity; hormone activity; and iron ion transmembrane transporter inhibitor activity. Involved in several processes, including cellular response to X-ray; cellular response to cytokine stimulus; and cellular response to lipid. Located in apical cortex; extracellular space; and intercalated disc. Used to study anemia and hepatocellular carcinoma. Biomarker of several diseases, including anemia (multiple); end stage renal disease; extrahepatic cholestasis; iron deficiency anemia; and liver disease (multiple). Human ortholog(s) of this gene implicated in hemochromatosis; hemochromatosis type 2B; and hepatocellular carcinoma. Orthologous to human HAMP (hepcidin antimicrobial peptide). [provided by Alliance of Genome Resources, Apr 2022]

Hamp 基因产物(1)

mRNA Protein Name
NM_053469.2 NP_445921.1 hepcidin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
22469696 RGD
involved in cellular response to X-ray IEP
IEP: 通过表达模式推断
17090718 RGD
involved in cellular response to bile acid IEP
IEP: 通过表达模式推断
19652645 RGD
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
23506423 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23506423 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
23506423 RGD
involved in intracellular iron ion homeostasis IDA
IDA: 通过直接分析推断
14592944 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
22364558 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IMP
IMP: 通过突变表型推断
24424338 RGD
involved in response to erythropoietin IEP
IEP: 通过表达模式推断
18306987 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
19008338 RGD
involved in response to iron ion starvation IEP
IEP: 通过表达模式推断
21115976 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
24998947 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
21430246 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical cortex IDA
IDA: 通过直接分析推断
15684344 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
24895335 RGD
located in intercalated disc IDA
IDA: 通过直接分析推断
17363462 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hepcidin

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990617 Anti-Hepcidin/HAMP Antibody (LY2787106) Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05995 HAMP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24724 Hamp Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990429 Anti-Hepsin Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hamp NCBI NCBI:57817
Mus musculus Hamp NCBI NCBI:84506
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