2. Gene
  3. DCLK3 - doublecortin like kinase 3 Gene

DCLK3 - doublecortin like kinase 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：双皮质素样激酶 3

种属: Homo sapiens

同用名: CLR; DCK3; DCDC3C; DCAMKL3

基因 ID: 85443 | 基因类型: protein coding

关于 DCLK3

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:36,712,421-36,764,553 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 22 paralogues. Biased expression in testis (RPKM 2.2), brain (RPKM 0.5) and 6 other tissues.

功能概要

预测启用蛋白激酶活性。预计参与肽基丝氨酸磷酸化。预计在蛋白质定位到细胞核的负调节上游或负调节内起作用。预计在细胞质和细胞核中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of protein localization to nucleus. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DCLK3 基因产物(2)

mRNA Protein Name
NM_001394672.2 NP_001381601.1 serine/threonine-protein kinase DCLK3 isoform 1
NM_033403.1 NP_208382.1 serine/threonine-protein kinase DCLK3 isoform 2

DCLK3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (356 - 613)

  • 0
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  • 200
  • 300
  • 400
  • 500
  • 600
  • 648 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase DCLK3

CLICK-I,II-related

关联疾病

疾病名称 别名
Multidrug-Resistant Tuberculosis

Tuberculosis, Multidrug-Resistant

Tuberculosis Multidrug-Resistant
Neutropenia, Severe Congenital, X-Linked

X-Linked Severe Congenital Neutropenia

XLN

SCNX

Severe Congenital Neutropenia X-Linked

Neutropenia, Congenital, Severe, X-Linked
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03580 DCLK3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus DCLK3 VGNC VGNC:59331
Mus musculus DCLK3 MGD MGI:3039580
Felis catus DCLK3 VGNC VGNC:61369
Macaca mulatta DCLK3 VGNC VGNC:71671
Rattus norvegicus DCLK3 RGD RGD:1309232
Canis familiaris DCLK3 VGNC VGNC:39805
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