2. Gene
  3. Enpp1 - ectonucleotide pyrophosphatase/phosphodiesterase 1 Gene

Enpp1 - ectonucleotide pyrophosphatase/phosphodiesterase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pc1; Npps

基因 ID: 85496 | 基因类型: protein coding

关于 Enpp1

功能概要

Enables phosphodiesterase I activity. Involved in several processes, including brain development; cellular response to cAMP; and cellular response to mechanical stimulus. Located in several cellular components, including dendrite; neuronal cell body; and synapse. Biomarker of aortic valve disease 1. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; obesity; ossification of the posterior longitudinal ligament of spine; and type 2 diabetes mellitus. Orthologous to human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Enpp1 基因产物(1)

mRNA Protein Name
NM_053535.2 NP_445987.2 ectonucleotide pyrophosphatase/phosphodiesterase family member 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphodiesterase I activity IDA
IDA: 通过直接分析推断
17187902 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to acidic pH IEP
IEP: 通过表达模式推断
26033523 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
21168404 RGD
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
24157151 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
24157151 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
18565716 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
18565716 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
18565716 RGD
involved in liver development IEP
IEP: 通过表达模式推断
10231554 RGD
involved in olfactory bulb development IEP
IEP: 通过表达模式推断
18565716 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
26746151 RGD
involved in striatum development IEP
IEP: 通过表达模式推断
18565716 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical dendrite IDA
IDA: 通过直接分析推断
17046728 RGD
located in basal dendrite IDA
IDA: 通过直接分析推断
17046728 RGD
located in cell body IDA
IDA: 通过直接分析推断
22086174 RGD
located in cell projection IDA
IDA: 通过直接分析推断
22086174 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
17046728 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
19474315 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ectonucleotide pyrophosphatase/phosphodiesterase family member 1

E-NPP 1

phosphodiesterase I/nucleotide pyrophosphatase 1

plasma-cell membrane glycoprotein PC-1

相关产品

Pre-clinical Phase
生物活性分子 (38)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-129490 Enpp-1-IN-1 Inhibitor 99.19% 否
HY-147389 Enpp-1-IN-14 Inhibitor 99.67% 否
HY-143256 Enpp-1-IN-12 Inhibitor 99.28% 否
HY-139362 Enpp-1-IN-2 Inhibitor 99.51% 否
HY-155457 Enpp-1-IN-19 99.28% 否
HY-153335 Enpp-1-IN-16 Inhibitor 98.46% 否
HY-158791 Enpp-1-IN-21 Inhibitor 99.07% 否
HY-163343 Enpp-1-IN-20 98.06% 否
HY-143254 Enpp-1-IN-10 Inhibitor 98.64% 否
HY-176708 ISM5939 Inhibitor / 否
HY-141831 STF-1084 Inhibitor 99.40% 否
HY-145063 Enpp-1-IN-5 Inhibitor 98.16% 否
HY-176296 Vizenpistat Inhibitor / 否
HY-169804 ENPP3 Inhibitor 1 Inhibitor 99.43% 否
HY-143255 Enpp-1-IN-11 Inhibitor / 否
HY-145062 Enpp-1-IN-4 Inhibitor / 否
HY-145064 Enpp-1-IN-6 Inhibitor / 否
HY-145065 Enpp-1-IN-7 Inhibitor / 否
HY-145069 Enpp-1-IN-8 Inhibitor / 否
HY-145070 Enpp-1-IN-9 Inhibitor / 否
HY-147998 Enpp-1-IN-13 Inhibitor / 否
HY-153334 Enpp-1-IN-15 Inhibitor / 否
HY-153398 Enpp-1-IN-17 Inhibitor / 否
HY-157522 NCI-14465 Inhibitor / 否
HY-162911 Enpp-1-IN-22 Inhibitor / 否
HY-162912 Enpp-1-IN-23 Inhibitor / 否
HY-168147 Enpp-1-IN-24 Inhibitor / 否
HY-168491 Enpp-1-IN-25 / 否
HY-172527 CD73-IN-20 Inhibitor / 否
HY-172528 Enpp-1/3-IN-1 Inhibitor / 否
HY-175047 Enpp-1-IN-26 Inhibitor / 否
HY-175478 Enpp-1-IN-27 / 否
HY-176828 Enpp-1-IN-28 Inhibitor / 否
HY-176874 Enpp-1-IN-29 Inhibitor / 否
HY-RS04387 ENPP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-156205 CdnP-IN-1 Inhibitor / 否
HY-RS16545 Enpp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22977 Enpp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991677 Efmirenpase alfa / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Enpp1 NCBI NCBI:5167
Canis familiaris Enpp1 NCBI NCBI:100856150
Mus musculus Enpp1 NCBI NCBI:18605
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