2. Gene
  3. Rfc1 - replication factor C subunit 1 Gene

Rfc1 - replication factor C subunit 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Recc1

基因 ID: 89809 | 基因类型: protein coding

关于 Rfc1

功能概要

Enables double-stranded DNA binding activity; protein domain specific binding activity; and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Located in cytoplasm and nucleolus. Part of protein-containing complex. Human ortholog(s) of this gene implicated in West Nile fever. Orthologous to human RFC1 (replication factor C subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Rfc1 基因产物(1)

mRNA Protein Name
NM_053547.1 NP_445999.1 replication factor C subunit 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
11356826 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
9826522 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7729533 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11356826 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9826522 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
9826522 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9677428 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
9826522 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
11356826 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11356826 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

replication factor C subunit 1

replication factor C (activator 1) 1

replication factor C 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11865 RFC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13047 SLC19A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22297 Rfc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28820 Rfc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rfc1 NCBI NCBI:5981
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