2. Gene
  3. Socs3 - suppressor of cytokine signaling 3 Gene

Socs3 - suppressor of cytokine signaling 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cish3; Ssi-3; Socs-3

基因 ID: 89829 | 基因类型: protein coding

关于 Socs3

功能概要

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity and phosphotyrosine residue binding activity. Involved in several processes, including receptor signaling pathway via JAK-STAT; response to estradiol; and response to steroid hormone. Located in cytoplasm. Biomarker of obesity; status epilepticus; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in atopic dermatitis 4. Orthologous to human SOCS3 (suppressor of cytokine signaling 3). [provided by Alliance of Genome Resources, Apr 2022]

Socs3 基因产物(1)

mRNA Protein Name
NM_053565.1 NP_446017.1 suppressor of cytokine signaling 3
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
11867182 RGD
involved in cell surface receptor signaling pathway via JAK-STAT IDA
IDA: 通过直接分析推断
12239110 RGD
involved in cellular response to thyrotropin-releasing hormone IEP
IEP: 通过表达模式推断
10707961 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
10707961 RGD
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
12239110 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
17405912 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
18424750 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
18325991 RGD
involved in response to food IEP
IEP: 通过表达模式推断
12163036 RGD
involved in response to gamma radiation IEP
IEP: 通过表达模式推断
14751512 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
10998044 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
11133009 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16125475 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
15192048 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18424750 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
12239110 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
12107179 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
18325991 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17394460 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

suppressor of cytokine signaling 3

cytokine inducible SH2-containing protein 3

cytokine-inducible SH2 protein 3

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-155335 FPR2 agonist 3 Agonist 99.39% 否
HY-RS16260 Socs3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-117511 HJC0123 / 否
HY-169908 STAT3-IN-37 Inhibitor / 否
HY-172402 Vasoactive intestinal peptide / 否
HY-RS13554 SOCS3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23359 Socs3 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990001 Anti-Mouse IL-10 Antibody (JES5-2A5) Inhibitor ≥95.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Socs3 NCBI NCBI:9021
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