1. Membrane Transporter/Ion Channel
  2. Na+/K+ ATPase
  3. Gitoxin

Gitoxin 是 Na+/K+-ATPase 的抑制剂,是Digitoxin 的降解代谢物,因ZOH 基团靠近C-17β 位置,可改善药代动力学和药效学数据。

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Gitoxin Chemical Structure

Gitoxin Chemical Structure

CAS No. : 4562-36-1

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Other Forms of Gitoxin:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably[1].

分子量

780.94

Formula

C41H64O14

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Gitoxin
目录号:
HY-136933
需求量: