1. Metabolic Enzyme/Protease
  2. FABP
  3. LDN-0088050

LDN-0088050 

目录号: HY-100467
产品使用指南

LDN 0088050 是一种选择性的脂肪酸结合蛋白 (AFABP, FABP4) 抑制剂,FABP4、FABP3 的 Ki 值分别为 0.29、1.3 μM. LDN 0088050 结合 FABP4 的Kd 值为 2.05 μM。

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LDN-0088050 Chemical Structure

LDN-0088050 Chemical Structure

CAS No. : 353484-30-7

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Description

LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1].

IC50 & Target

Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]
Kd: 2.05 μM (FABP4)[1]

In Vitro

LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1].

Molecular Weight

372.26

Formula

C₁₉H₁₈BrNO₂

CAS No.

353484-30-7

SMILES

OC(C(C1C2C=CC1)N3CC4C(C=CC4)C5=CC(Br)=CC2=C35)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
LDN-0088050
目录号:
HY-100467
需求量:

LDN-0088050

Cat. No.: HY-100467