2. Immunology/Inflammation
  3. CD28
  4. Lulizumab pegol

Lulizumab pegol  (Synonyms: BMS-931699)

目录号: HY-P99717

摩尔计算器

Lulizumab pegol (BMS-931699) 是一种抗 CD28 抗体拮抗剂。Lulizumab pegol 可有效抑制 T 细胞增殖。Lulizumab pegol 可用于肾移植和自身免疫性疾病的研究。

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Lulizumab pegol Chemical Structure

Lulizumab pegol Chemical Structure

CAS No. : 1421830-13-8

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Lulizumab pegol 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Lulizumab pegol (BMS-931699) is an anti-CD28 antibody antagonist. Lulizumab pegol effectively inhibits T-cell proliferation and it can be used for the reseach of kidney transplantation and autoimmunity disease[1].

体外研究
(In Vitro)

BMS-931699 通过生物大分子相互作用分析系统显示出对 T 细胞增殖的 Kd 为 0.41 nM[1]。
BMS-931699 通过混合淋巴细胞反应 (MLR) 诱导的 T 细胞增殖的 EC50 为 2.9 nM 以及对全血中 CD28 受体占用 (RO) 的 EC50 为 4.4 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lulizumab pegol 相关抗体:
Clinical Trial
CAS 号
储存方式

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纯度 & 产品资料
参考文献

Lulizumab pegol 相关分类

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Keywords:

Lulizumab pegol1421830-13-8BMS-931699BMS931699BMS 931699CD28kidney transplantationlupusT-cellMLRreceptor occupancyInhibitorinhibitorinhibit

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