2. GPCR/G Protein
  3. GCGR
  4. Oxyntomodulin (bovine, porcine) (TFA)

Oxyntomodulin (bovine, porcine) (TFA)  (Synonyms: Glucagon-37 (bovine, porcine) (TFA))

目录号: HY-P1144A
产品使用指南

摩尔计算器

Oxyntomodulin (bovine, porcine) TFA 是一种含 37 个氨基酸的肽激素，是胰高血糖素样肽 1 (GLP-1) 受体激动剂。

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Custom Peptide Synthesis

Oxyntomodulin (bovine, porcine) (TFA) Chemical Structure

Oxyntomodulin (bovine, porcine) (TFA) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Oxyntomodulin (bovine, porcine) (TFA) 的其他形式现货产品:

Customer Review

Other Forms of Oxyntomodulin (bovine, porcine) (TFA):

Oxyntomodulin (bovine, porcine) (TFA) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oxyntomodulin (bovine, porcine) TFA, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].

体外研究
(In Vitro)

Oxyntomodulin (bovine, porcine) is a peptide hormone released from the gut in post-prandial state that activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR) resulting in superior body weight lowering to selective GLP1R agonists. Oxyntomodulin is mainly produced in gut endocrine L-cells by processing of the preproglucagon precursor by prohormone convertase 1/3. Oxyntomodulin is a full agonist in cell lines over expressing the human GLP1R and GCGR-mediated cAMP accumulation although with reduced affinity compared to GLP-1 and glucagon[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Oxyntomodulin (bovine, porcine) (TFA) 相关抗体:
Clinical Trial
Formula

C192H295N59O60S.xC2HF3O2
Sequence Shortening

HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA
中文名称

胃泌酸调节素三氟乙酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Oxyntomodulin (bovine, porcine) (TFA) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxyntomodulin (bovine, porcine) (TFA)Glucagon-37 (bovine, porcine) (TFA)胃泌酸调节素三氟乙酸盐GCGRGlucagon ReceptorInhibitorinhibitorinhibit

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目录号：
HY-P1144A
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