2. Immunology/Inflammation
  3. COX
  4. Plantanone B

Plantanone B  (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

目录号: HY-N8167
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摩尔计算器

Plantanone B 是一种中等抗氧化剂，IC50 为 169.8±5.2 μM。Plantanone B 具有显著的绵羊 COX-1 抑制活性和中等的 COX-2 抑制活性。Plantanone B 有研究炎症相关疾病的潜力。

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Plantanone B Chemical Structure

Plantanone B Chemical Structure

CAS No. : 55780-30-8

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Plantanone B 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

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COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1].

IC50 & Target[1]

Ovine COX-1

21.78±0.2 μM (IC50)

Ovine COX-2

44.01±0.42 μM (IC50)

体外研究
(In Vitro)

The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1].
Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1].
.Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Plantanone B 相关抗体:
分子量

756.66

Formula

C33H40O20
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Plantanone B 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Plantanone B55780-30-8Kaempferol 3-O-rhamnosylgentiobiosideCOXCyclooxygenaseantioxidant-agentCOX-2COX-1inflammationInhibitorinhibitorinhibit

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