1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Purine nucleoside phosphorylase, Microorganism

Purine nucleoside phosphorylase, Microorganism  (Synonyms: PNP)

目录号: HY-P2724
COA 产品使用指南

Purine nucleoside phosphorylase, Microorganism (PNP) 是嘌呤代谢中的关键酶,参与嘌呤挽救途径。Purine nucleoside phosphorylase 缺乏导致 T 细胞功能受损。在无机正磷酸盐作为第二底物的存在下,Purine nucleoside phosphorylase 催化核糖和脱氧核糖核苷的糖苷键断裂,生成嘌呤碱和核糖(脱氧核糖)-1-磷酸。

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Purine nucleoside phosphorylase, Microorganism Chemical Structure

Purine nucleoside phosphorylase, Microorganism Chemical Structure

CAS No. : 9030-21-1

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  • 生物活性

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生物活性

Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vitro: 

H2O 中的溶解度 : ≥ 100 mg/mL

* "≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
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体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

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给药剂量

mg/kg

动物的平均体重

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每只动物的给药体积

μL

动物数量

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参考文献

Purine nucleoside phosphorylase, Microorganism 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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