1. 重组蛋白
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  3. Inhibitory Checkpoint Molecules Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  4. B7-2/CD86
  5. B7-2/CD86 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His)

B7-2/CD86 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His)

目录号: HY-P75493
产品使用指南

B7-2/CD86 蛋白通过破坏 CD86 簇形成、调节 T 细胞反应和影响免疫激活来负调节 T 细胞激活。B7-2/CD86 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His) 是重组的 B7-2/CD86 蛋白,由 HEK293 表达,带有 C-His 标签。B7-2/CD86 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His) 全长 239 个氨基酸,分子量为 54-66 kDa。

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描述

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 239 a.a., with molecular weight of 54-66 kDa.

研究背景

B7-2/CD86 蛋白通过破坏 CD86 簇的形成,充当 T 细胞激活的负调节因子。通过这种干扰,它可以调节 T 细胞反应并在调节免疫激活中发挥作用。

种属

Rhesus Macaque; Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

Q9BDM4 (M1-H239)

基因 ID

714390  [NCBI]

蛋白结构
N-term
B7-2 (M1-H239)
Accession # Q9BDM4
His
C-term
同用名
Activation B7-2 antigen; B70; BU63; CD86; CD28LG2
分子量

54-66 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)
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HY-P75493
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