2. 重组蛋白
  3. Cytokines and Growth Factors CAR-T related Proteins CD Antigens
  4. TNF Superfamily T Cell CD Proteins Macrophage CD Proteins Erythrocyte CD Proteins
  5. TNF Receptor Superfamily CD30
  6. CD30/TNFRSF8 蛋白, Mouse (258a.a, HEK293, His)

CD30/TNFRSF8 蛋白, Mouse (258a.a, HEK293, His)

目录号: HY-P76221
产品使用指南

CD30/TNFRSF8 蛋白（TNFSF8/CD30L 受体）关键调节细胞生长和淋巴母细胞转化。它激活 NF-kappa-B 信号传导、调节基因表达并促进多种细胞过程。与关键信号分子（TRAF1、TRAF2、TRAF3 和 TRAF5）的相互作用强调了其在介导细胞反应和调节功能的重要细胞内途径中的重要性。CD30/TNFRSF8 蛋白, Mouse (258a.a, HEK293, His) 是重组的 CD30/TNFRSF8 蛋白，由 HEK293 表达，带有 C-His 标签。CD30/TNFRSF8 蛋白, Mouse (258a.a, HEK293, His) 全长 258 个氨基酸，分子量约为 ~26.6 KDa。

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1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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描述

CD30/TNFRSF8 Protein, the TNFSF8/CD30L receptor, critically regulates cellular growth and lymphoblast transformation. It activates NF-kappa-B signaling, modulating gene expression and contributing to diverse cellular processes. Interactions with key signaling molecules (TRAF1, TRAF2, TRAF3, and TRAF5) underscore its significance in mediating essential intracellular pathways for cellular responses and regulatory functions. CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is the recombinant mouse-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is 258 a.a., with molecular weight of ~26.6 KDa.
研究背景

CD30/TNFRSF8 蛋白作为 TNFSF8/CD30L 的受体，在细胞生长的调节和活化的淋巴母细胞的转化中发挥着关键作用。此外，它还通过激活 NF-kappa-B 信号传导参与基因表达的调节，从而促进多种细胞过程。与关键信号分子（包括 TRAF1、TRAF2、TRAF3 和 TRAF5）的相互作用进一步强调了其在介导细胞反应和调节功能所必需的细胞内途径中的重要性。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

Q60846 (M1-T258)
基因 ID

21941  [NCBI]
蛋白结构
N-term
CD30 (M1-T258)
Accession # Q60846
His
C-term
同用名
CD30L receptor; Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen
分子量

Approximately 26.6 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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