CDO 蛋白, Human (HEK293, His)

CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDO Protein, Human (HEK293, His) is 918 a.a., with molecular weight of 120-135 kDa.

CDO（细胞粘附分子相关/癌基因下调）是细胞表面受体复合物的一个组成部分，对于介导肌肉前体细胞之间的细胞间相互作用至关重要。它对促进肌原细胞的分化具有重要作用。CDO 是包括 BOC、CDON、NEO1、钙粘蛋白和 CTNNB1 在内的复合体的一部分，强调了它参与复杂的信号网络。此外，CDO 与 NTN3、PTCH1 和 GAS1 相互作用，表明它与多种信号通路相关。值得注意的是，CDO 与重要的信号分子（如 DHH、IHH 和 SHH）结合，强调其参与对细胞发育和组织模式至关重要的途径。CDO 的多方面相互作用凸显了其作为发育过程中协调细胞过程的关键调节剂的作用。（参考：提供的资料）

Human

HEK293

C-6*His

Q4KMG0 (D26-P943)

50937  [NCBI]

DLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPP

120-135 kDa

Greater than 85% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.